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855275P

Avanti

08:0 Lyso PC

1-octanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

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Synonym(s):
1-octanoyl-sn-glycero-3-phosphocholine; PC(8:0/0:0)
Empirical Formula (Hill Notation):
C16H34NO7P
CAS Number:
45287-18-1
Molecular Weight:
383.42
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 25 mg (855275P-25mg)

manufacturer/tradename

Avanti Polar Lipids 855275P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCC)=O

General description

Lysophosphatidylcholine (Lyso-PC) is a constituent of blood plasma, vascular tissue and lipoproteins. It is a bioactive proinflammatory lipid, produced on pathological response.

Biochem/physiol Actions

Lysophosphatidylcholine (Lyso-PC) is linked to inflammatory diseases and atherosclerosis. It enhances the expression of genes for growth factors and cellular adhesion molecules.

Packaging

5 mL Clear Glass Sealed Ampule (855275P-25mg)

Certificates of Analysis (COA)

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Development and validation of a UHPLC-ESI-MS/MS method for the simultaneous quantification of mammal lysophosphatidylcholines and lysophosphatidylethanolamines in serum
Suarez-Garcia S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1055, 86-97 (2017)
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells
Wong JT, et al.
Test, 273(12), 6830-6836 (1998)
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)
R E Stafford et al.
Biochemistry, 28(12), 5113-5120 (1989-06-13)
The critical micelle concentration (cmc) of several lysophospholipids and of a lysophospholipid analogue was determined from surface tension measurements using the maximum bubble pressure method and/or 31P NMR. The use of the maximum bubble pressure method has now been extended

Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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