852758P
Avanti
C18(Plasm)-18:1 PE
1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder
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1-O-1′-(Z)-octadecenyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; GPEtn(18:0p/18:1(9Z)); 110645
C41H80NO7P
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Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (852758P-10mg)
pkg of 1 × 5 mg (852758P-5mg)
manufacturer/tradename
Avanti Polar Lipids 852758P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O
General description
Phosphatidylethanolamine is an amino phospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in the biological membranes. Phosphatidylethanolamine is found in nervous tissue.
Application
C18(Plasm)-18:1 PE has been used for lipid purification and fatty acid extraction. It has also been used for lipopolysaccharide (LPS)-mediated beta rich prion protein PrPβ conversion.
Biochem/physiol Actions
Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.
Packaging
5 mL Amber Glass Screw Cap Vial (852758P-5mg)
5 mL Amber Glass Sealed Ampule (852758P-10mg)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Lipopolysaccharide induced conversion of recombinant prion protein
Prion, 8(2), 221-232 (2014)
The Membranes of Cells (2016)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry
Molecular Genetics and Metabolism, 120(3), 255-268 (2017)
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