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850725C

Avanti

18:1 (Δ9-Cis) PE (DOPE)

Avanti Polar Lipids

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Synonym(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; DOPE; PE(18:1(9Z)/18:1(9Z)); 110635
Empirical Formula (Hill Notation):
C41H78NO8P
CAS Number:
4004-05-1
Molecular Weight:
744.03
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, chloroform solution

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850725C-25mg)
pkg of 2 × 20 mL (850725C-1g)
pkg of 2 × 4 mL (850725C-200mg)
pkg of 5 × 4 mL (850725C-500mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (850725C-25mg)
25 mg/mL (850725C-1g)
25 mg/mL (850725C-200mg)
25 mg/mL (850725C-500mg)

application(s)

advanced drug delivery

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1

InChI key

MWRBNPKJOOWZPW-NYVOMTAGSA-N

Application

18:1 (Δ9-Cis) PE (DOPE) has been used:
  • as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS)
  • to investigate its impact on antiphosphatidylethanolmine (aPE) enzyme-linked immunosorbent assay (ELISA)
  • to measure its monolayer spontaneous curvature C0s

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850725C-1g)
5 mL Clear Glass Sealed Ampule (850725C-200mg)
5 mL Clear Glass Sealed Ampule (850725C-25mg)
5 mL Clear Glass Sealed Ampule (850725C-500mg)

also commonly purchased with this product

Product No.
Description
Pricing

700000P

Cholesterol (ovine), Avanti Polar Lipids

710335C

18:1 Cardiolipin, Avanti Polar Lipids

810145C

18:1 NBD PE, Avanti Polar Lipids

810150C

18:1 Liss Rhod PE, Avanti Polar Lipids

840034C

16:0-18:1 PS (POPS), Avanti Polar Lipids

840035C

18:1 PS (DOPS), Avanti Polar Lipids

840455P

16:0 PG, Avanti Polar Lipids

840457C

16:0-18:1 PG, Avanti Polar Lipids

840475C

18:1 (Δ9-Cis) PG, Avanti Polar Lipids

840875C

18:1 PA, Avanti Polar Lipids

850155P

18:1 PI(4,5)P2, Avanti Polar Lipids

850345C

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

850345P

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

850355C

16:0 PC (DPPC), Avanti Polar Lipids

850375C

18:1 (Δ9-Cis) PC (DOPC), Avanti Polar Lipids

850375P

18:1 (Δ9-Cis) PC (DOPC), Avanti Polar Lipids

850457C

16:0-18:1 PC, Avanti Polar Lipids

850457P

16:0-18:1 PC, Avanti Polar Lipids

850725P

18:1 (Δ9-Cis) PE (DOPE), Avanti Polar Lipids

850757C

16:0-18:1 PE, Avanti Polar Lipids

870273C

18:1 Biotinyl Cap PE, Avanti Polar Lipids 870273C

890890C

18:1 TAP (DOTAP), Avanti Polar Lipids

840051C

Egg PC, Avanti Polar Lipids

860061C

Egg SM, Avanti Polar Lipids

880130C

18:1 PEG2000 PE, Avanti Polar Lipids 880130C

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Differential dependencies on [Ca 2+] and temperature of the monolayer spontaneous curvatures of DOPE, DOPA and cardiolipin: effects of modulating the strength of the inter-headgroup repulsion
Chen YF, et al.
Soft Matter, 11(20), 4041-4053 (2015)
Matthias Dittrich et al.
Langmuir : the ACS journal of surfaces and colloids (2018-09-01)
Colloidal nucleic acid carrier systems based on cationic lipids are a promising pharmaceutical tool in the implementation of gene therapeutic strategies. This study demonstrates the complex behavior of DNA at the lipid-solvent interface facilitating structural changes of the lyotropic liquid-crystalline
Jamie Burrell et al.
Langmuir : the ACS journal of surfaces and colloids, 33(44), 12804-12813 (2017-10-06)
Oxylipins, or fatty aldehydes, are a class of molecules produced from membrane lipids as a result of oxidative stress or enzyme-mediated peroxidation. Here we report the effects of two biologically important fatty aldehydes, trans,trans-2,4-decanedienal (DD) and cis-11-hexadecenal (HD), on the
The outcome of ELISA for antiphosphatidylethanolamine antibodies is dependent on the composition of phosphatidylethanolamine
Hou S, et al.
Journal of Immunological Methods, 440, 27-34 (2017)
Mariya Chavarha et al.
Biophysical journal, 104(3), 594-603 (2013-02-28)
The hydrophobic surfactant proteins, SP-B and SP-C, greatly accelerate the adsorption of the surfactant lipids to an air/water interface. Previous studies of factors that affect curvature suggest that vesicles may adsorb via a rate-limiting structure with prominent negative curvature, in
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