850697P
Avanti
06:0 PE
1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, powder
Synonym(s):
PE(6:0/6:0)
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About This Item
Empirical Formula (Hill Notation):
C17H34NO8P
CAS Number:
Molecular Weight:
411.43
UNSPSC Code:
51191904
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850697P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850697P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O
InChI
1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1
InChI key
PELYUHWUVHDSSU-OAHLLOKOSA-N
General description
06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.
Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.
Application
06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
- as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
- as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
- as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).
Biochem/physiol Actions
06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.
Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.
Packaging
5 mL Clear Glass Sealed Ampule (850697P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
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Find documentation for the products that you have recently purchased in the Document Library.
Crystallographic identification of lipid as an integral component of the epitope of HIV broadly neutralizing antibody 4E10
Irimia A, et al.
Immunity, 44(1), 21-31 (2016)
Liquid chromatographic analysis of milk phospholipids with on-line pre-concentration
Fagan P, et al.
Journal of Chromatography A, 1054(1-2), 241-249 (2004)
S F Martin et al.
Biochemistry, 39(12), 3410-3415 (2000-03-22)
The phosphatidylcholine-preferring phospholipase C from Bacillus cereus (PLC(Bc)) is a 28.5 kDa enzyme with three zinc ions in its active site. The roles that a number of amino acid residues play as zinc ligands and in binding and catalysis have
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL
Shingo Mineta et al.
Journal of bioscience and bioengineering, 119(2), 123-130 (2014-08-20)
Streptomyces sanglieri extracellularly produces a glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP). The gene encoding the enzyme was found to consist of a 2124-bp ORF, which codes for an N-terminal 48 residue signal peptide required for secretion and a 660 amino acid mature protein
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