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About This Item
Empirical Formula (Hill Notation):
C20H42O3
CAS Number:
Molecular Weight:
330.55
UNSPSC Code:
12161902
NACRES:
NA.25
Product Name
(2S,3S)-Phytantriol, Avanti Research™ - A Croda Brand 850555O
SMILES string
CC(C)CCCC(C)CCCC(C)CCC[C@](C)(O)[C@@H](O)CO
InChI
1S/C20H42O3/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-20(5,23)19(22)15-21/h16-19,21-23H,6-15H2,1-5H3
InChI key
CGIHFIDULQUVJG-UHFFFAOYSA-N
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 25 mg (850555O-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850555O
shipped in
dry ice
storage temp.
−20°C
General description
Phytantriol (3,7,11,15-tetramethylhexadecane-1,2,3-triol) is a lipid, that is mainly used in cosmetics.
The temperature−composition phase diagram of phytantriol/water mixtures is qualitatively similar to that of aqueous glycerol monooleate so its stability makes it an interesting alternative to exploit various applications of the cubic liquid crystalline phases.
Biochem/physiol Actions
Phytantriol (PT; 3,7,11,15- tetramethylhexadecane-1,2,3-triol) do not hydrolyze. It possesses good structural stability and higher purity over glycerylmonooleate (GMO) or GMO-based derivatives. It helps to retain moisture in the skin and serves as a penetration promoter, hence can be used in transdermal drug delivery.
Packaging
5 mL Clear Glass Sealed Ampule (850555O-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
Regulatory Information
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Internally self-assembled submicrometer emulsions stabilized by spherical nanocolloids: finding the free nanoparticles in the aqueous continuous phase
Salonen A, et al.
Langmuir, 26(11), 7981-7987 (2010)
Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior
Dong YD, et al.
Langmuir, 24(13), 6998-7003 (2008)
S B Rizwan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(1), 15-22 (2011-01-18)
Different delivery strategies to improve the immunogenicity of peptide/protein-based vaccines are currently under investigation. In this study, the preparation and physicochemical characterisation of cubosomes, a novel lipid-based particulate system currently being explored for vaccine delivery, was investigated. Cubosomes were prepared
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