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850535O

Avanti

9.7 MAG

Avanti Research™ - A Croda Brand

Synonym(s):

1-(9Z-hexadecenoyl)-rac-glycerol

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About This Item

Empirical Formula (Hill Notation):
C19H36O4
CAS Number:
37515-61-0
Molecular Weight:
328.49
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

oil

mol wt

328.49 g/mol

packaging

pkg of 10 × 0.1 g (with screw cap (850535O-1g))
pkg of 2 × 100 mg (with screw cap (850535O-200mg))
pkg of 5 × 100 mg (with screw cap (850535O-500mg))
pkg of 1 × 25 mg (with screw cap (850535O-25mg))

manufacturer/tradename

Avanti Research™ - A Croda Brand

technique(s)

protein sequencing: suitable

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCC/C=C\CCCCCCCC(OCC(O)CO)=O

InChI

1S/C19H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h7-8,18,20-21H,2-6,9-17H2,1H3/b8-7-

InChI key

KVYUBFKSKZWZSV-FPLPWBNLSA-N

General description

Monoacylglycerols (MAGs) can be synthesized by the esterification and transesterification of fatty acids and oils respectively.
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Application

9.7 MAG may be used as a host lipid to form lipidic cubic phase (LCP) for serial femtosecond crystallography in lipidic cubic phase (LCP-SFX).

Biochem/physiol Actions

Monoglycerides/monoacylglycerols are considered to be better emulsifiers when compared to diglycerides.

Packaging

5 mL PTFE Vial with Screw Cap (850535O-1g)
5 mL PTFE Vial with Screw Cap (850535O-200mg)
5 mL PTFE Vial with Screw Cap (850535O-25mg)
5 mL PTFE Vial with Screw Cap (850535O-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Emulsifiers (surfactants) and antioxidants as biscuit ingredients
Managed Care (Langhorne, Pa.) (2011)
Wei Liu et al.
Nature protocols, 9(9), 2123-2134 (2014-08-15)
We have recently established a procedure for serial femtosecond crystallography (SFX) in lipidic cubic phase (LCP) for protein structure determination at X-ray free-electron lasers (XFELs). LCP-SFX uses the gel-like LCP as a matrix for growth and delivery of membrane protein
Synthesis and characterization of monoacylglycerols through glycerolysis of ethyl esters derived from linseed oil by green processes
Hobuss CB, et al.
Royal Society of Chemistry Advances, 10, 2327-2336 (2020)
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that

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