850531O
Avanti
7.8 MAG
Avanti Research™ - A Croda Brand 850531O
Synonym(s):
1-(7Z-pentadecenoyl)-rac-glycerol
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C18H34O4
CAS Number:
Molecular Weight:
314.46
UNSPSC Code:
12352211
NACRES:
NA.25
Assay
>99% (TLC)
form
oil
mol wt
314.46 g/mol
packaging
pkg of 10 × 0.1 g (with screw cap (850531O-1g))
pkg of 2 × 100 mg (with screw cap (850531O-200mg))
pkg of 1 × 25 mg (with screw cap (850531O-25mg))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850531O
technique(s)
protein sequencing: suitable
shipped in
dry ice
storage temp.
−20°C
General description
Monoacylglycerols (MAGs) are glycerol esters, that can be produced by the glycerolysis of triglycerides and alkyl esters.
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.
Application
7.8 MAG has been used to form mesophase for PepTSt protein crystallization. It may also be used as a host lipid in MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex for crystallization by lipidic cubic phase (LCP) method.
Biochem/physiol Actions
Monoacylglycerols (MAGs) is non-toxic and does not show any adverse responses to mucous membranes at low concentration. Milk has MAG at low concentration. MAGs are used in several cosmetics products. It is also useful in plastic and textile industry.
Packaging
5 mL PTFE Vial with Screw Cap (850531O-1g)
5 mL PTFE Vial with Screw Cap (850531O-200mg)
5 mL PTFE Vial with Screw Cap (850531O-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
also commonly purchased with this product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
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Maria Martinez Molledo et al.
Structure (London, England : 1993), 26(3), 467-476 (2018-02-13)
Proton-dependent oligopeptide transporters (POTs) are important for uptake of dietary di- and tripeptides in many organisms, and in humans are also involved in drug absorption. These transporters accept a wide range of substrates, but the structural basis for how different peptide
Kumar Nagarathinam et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 7), 423-430 (2017-07-12)
The active efflux of antibiotics by multidrug-resistance (MDR) transporters is a major pathway of drug resistance and complicates the clinical treatment of bacterial infections. MdfA is a member of the major facilitator superfamily (MFS) from Escherichia coli and provides resistance
Synthesis and characterization of monoacylglycerols through glycerolysis of ethyl esters derived from linseed oil by green processes
Hobuss CB, et al.
Royal Society of Chemistry Advances, 10, 2327-2336 (2020)
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that
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