850454P
Avanti
16:0-14:0 PC
1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine, powder
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Synonym(s):
1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine; PMPC; PC(16:0/14:0)
Empirical Formula (Hill Notation):
C38H76NO8P
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850454P-25mg)
manufacturer/tradename
Avanti Polar Lipids 850454P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
General description
Phosphatidylcholine (PC) is an important component of the mucosal layer of the colon. 16:0-14:0 PC (PMPC/1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine) is the positional isomer of 1-myristoyl-2-palmitoyl-PC (MPPC).
Application
16:0-14:0 PC (1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine) may be used as an inhibitor for screening several recombinant human UDP-glucuronosyltransferases (UGTs).
Biochem/physiol Actions
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.
Packaging
5 mL Amber Glass Screw Cap Vial (850454P-25mg)
Certificates of Analysis (COA)
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Xin Gao et al.
Xenobiotica; the fate of foreign compounds in biological systems, 45(3), 197-206 (2014-09-27)
1.Endogenous compounds have been reported to be the regulators of UDP-glucuronosyltransferases (UGTs) isoforms. This study aims to investigate the regulatory effects of the activity of UGT isoforms by two important lipid components phosphatidylcholine (PC) and lysophosphatidylcholines (LPC) using in vitro
Integrative Medicine - E-Book (2017)
Hitoshi Matsuki et al.
International journal of molecular sciences, 14(2), 2282-2302 (2013-01-26)
Bilayers formed by phospholipids are frequently used as model biological membranes in various life science studies. A characteristic feature of phospholipid bilayers is to undergo a structural change called a phase transition in response to environmental changes of their surroundings.
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