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850408C

Avanti

4ME 16:0 PS

1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

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Synonym(s):
1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))
Empirical Formula (Hill Notation):
C46H89NO10PNa
CAS Number:
474967-76-5
Molecular Weight:
870.16
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (850408C-10mg)
pkg of 1 × 2.5 mL (850408C-25mg)

manufacturer/tradename

Avanti Polar Lipids 850408C

concentration

10 mg/mL (850408C-10mg)
10 mg/mL (850408C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O.[Na+]

Application

4ME 16:0 PS or 1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (DPhPS) is suitable for use:
  • in the preparation of planar lipid bilayers
  • as an internal standard in mass spectrometry for lipidomic analyses
  • in the preparation of black lipid membranes
  • as a substrate for phaiodactylipin enzyme

Packaging

5 mL Clear Glass Sealed Ampule (850408C-10mg)
5 mL Clear Glass Sealed Ampule (850408C-25mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Information

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Phaiodactylipin, a glycosylated heterodimeric phospholipase A2 from the venom of the scorpion Anuroctonus phaiodactylus
Valdez-Cruz NA, et al.
European Journal of Biochemistry, 271(8), 1453-1464 (2004)
A critical reassessment of penetratin translocation across lipid membranes
Barany-Wallje E, et al.
Biophysical Journal, 89(4), 2513-2521 (2005)
The early metabolomic response of adipose tissue during acute cold exposure in mice
Lu X, et al.
Scientific Reports, 7(1), 3455-3455 (2017)
Does the lipid environment impact the open-state conductance of an engineered beta-barrel protein nanopore?
Tomita N, et al.
Biochimica et Biophysica Acta - Biomembranes, 1828(3), 1057-1065 (2013)
Alessio Sacconi et al.
Langmuir : the ACS journal of surfaces and colloids, 34(40), 12183-12190 (2018-09-16)
Solid supported membranes (SSMs) are usually formed by an hybrid octadecanethiol/phosphatidylcholine (PC) bilayer supported by a gold electrode. Recently, it was shown that phosphatidylserine (PS) in place of PC can promote a more effective accumulation of lipid vesicles on the
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