850373C
Avanti
24:0 PC
1,2-dilignoceroyl-sn-glycero-3-phosphocholine, chloroform
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Synonym(s):
1,2-ditetracosanoyl-sn-glycero-3-phosphocholine; PC(24:0/24:0) ; 110929
Empirical Formula (Hill Notation):
C56H112NO8P
Recommended Products
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (850373C-25mg)
manufacturer/tradename
Avanti Polar Lipids 850373C
concentration
10 mg/mL (850373C-25mg)
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
General description
24:0 PC (1,2-dilignoceroyl-sn-glycero-3-phosphocholine) is a long-chain diacyl phospholipid, which has C24 saturated hydrocarbon chains. This lipid has a phosphatidylcholine (PC) headgroup.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
24:0 PC (1,2-dilignoceroyl-sn-glycero-3-phosphocholine) may be used:
- in short-chain micelles, longer-chain oriented multilayers and in Langmuir monolayers for structural studies
- as an acyl chain lipid in microbubble condensed droplets (MCDs) and characterization studies
- in phosphatidylcholine bilayer preparation for Raman spectroscopy studies
Biochem/physiol Actions
Phosphatidylcholine (PC) can prevent the penetrance of bacteria by acting as a surfactant. This phospholipid is capable of forming a strong bilayer.
Packaging
5 mL Clear Glass Sealed Ampule (850373C-25mg)
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Description
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Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
易制毒化学品（2类）
危险化学品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Inflammatory Bowel Disease
Parian AM, et al.
Integrative Medicine, 501-516 (2018)
A A Dmitriev et al.
The journal of physical chemistry. B, 119(51), 15613-15622 (2015-11-27)
Raman scattering of five phosphatidylcholines [1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 1,2-dilinoleoyl-sn-glycero-3-phosphocholine (DLPC), and 1,2-dilignoceroyl-sn-glycero-3-phosphocholine (PC24)] was studied in a wide temperature range. These phospholipid bilayers differ in the temperature of the gel-fluid transition Tm (from -57 to +80 °C)
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
Paul A Mountford et al.
Langmuir : the ACS journal of surfaces and colloids, 31(16), 4627-4634 (2015-04-09)
This study explored the thermal conditions necessary for the vaporization of superheated perfluorocarbon nanodrops. Droplets C3F8 and C4F10 coated with a homologous series of saturated diacylphosphatidylcholines were formed by condensation of 4 μm diameter microbubbles. These drops were stable at
S Zheng et al.
Biophysical journal, 80(4), 1837-1850 (2001-03-22)
Vpu is an 81 amino acid integral membrane protein encoded by the HIV-1 genome with a N-terminal hydrophobic domain and a C-terminal hydrophilic domain. It enhances the release of virus from the infected cell and triggers degradation of the virus
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