850360P
Avanti
17:0 PC
1,2-diheptadecanoyl-sn-glycero-3-phosphocholine, powder
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All Photos(2)
Synonym(s):
PC(17:0/17:0)
Empirical Formula (Hill Notation):
C42H84NO8P
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850360P-200mg)
pkg of 1 × 25 mg (850360P-25mg)
manufacturer/tradename
Avanti Polar Lipids 850360P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O)=O
InChI
1S/C42H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3
InChI key
RTWAYAIMWLNAJW-UHFFFAOYSA-N
General description
Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the membrane. The fatty acids in the sn-1 and sn-2 positions of PCs are attached to a glycerol molecule covalently with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
17:0 PC (1,2-diheptadecanoyl-sn-glycero-3-phosphocholine) has been used:
- as an internal standard for phospholipids in fatty acid analysis
- as a component in the extraction mixture for lipid extraction from frozen leaf tissue
- as an internal standard and a component in methanol: methyl tert-butyl ether (MTBE) extraction buffer for the determination of metabolite levels in tumor and normal tissues using gas chromatography-mass spectrometrometer (GC-MS)
Biochem/physiol Actions
Phosphatidylcholines (PCs) serve as a major source for eicosanoids.
Packaging
5 mL Amber Glass Screw Cap Vial (850360P-200mg)
5 mL Amber Glass Screw Cap Vial (850360P-25mg)
also commonly purchased with this product
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Certificates of Analysis (COA)
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Piotr Popławski et al.
Biochimica et biophysica acta. Molecular basis of disease, 1863(3), 744-752 (2016-12-26)
Cellular metabolism of renal cell carcinoma (RCC) tumors is disturbed. The clinical significance of these alterations is weakly understood. We aimed to find if changes in metabolic pathways contribute to survival of RCC patients. 35 RCC tumors and matched controls
Kristin A Marks et al.
Prostaglandins, leukotrienes, and essential fatty acids, 89(2-3), 89-96 (2013-06-20)
Sex differences in monounsaturated fatty acid (MUFA) levels suggest ovarian hormones may affect MUFA biosynthesis. Sprague-Dawley rats (8 weeks of age) were ovariectomized or sham operated with ovariectomized rats implanted with a constant-release hormone pellet providing 17β-estradiol, progesterone, both or
Dawid Perlikowski et al.
Frontiers in plant science, 7, 1027-1027 (2016-08-04)
Drought tolerant plant genotypes are able to maintain stability and integrity of cellular membranes in unfavorable conditions, and to regenerate damaged membranes after stress cessation. The profiling of cellular glycerolipids during drought stress performed on model species such as Arabidopsis
Taly Lapidot-Cohen et al.
Current protocols in plant biology, 5(2), e20109-e20109 (2020-04-29)
Lipids are fascinating due to their chemical diversity, which is especially vast in the plant kingdom thanks to the high plasticity of the plant biosynthetic machinery. Lipidomic studies aim to simultaneously analyze a large number of lipid compounds of diverse
Joanna Bogusławska et al.
Cancers, 11(12) (2019-11-24)
Metabolic reprogramming is one of the hallmarks of renal cell cancer (RCC). We hypothesized that altered metabolism of RCC cells results from dysregulation of microRNAs targeting metabolically relevant genes. Combined large-scale transcriptomic and metabolic analysis of RCC patients tissue samples
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