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About This Item
Empirical Formula (Hill Notation):
C19H42NO4P
CAS Number:
Molecular Weight:
379.51
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
MAPCHO™-14, n-tetradecylphosphocholine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (850338P-1g), pkg of 1 × 10 g (850338P-10g)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850338P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCCCC
InChI
1S/C19H42NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-23-25(21,22)24-19-17-20(2,3)4/h5-19H2,1-4H3
InChI key
BETUMLXGYDBOLV-UHFFFAOYSA-N
General description
MAPCHO™-14 is a fos-choline-based zwitterionic detergent.
Tetradecylphosphocholine is a structural analog of myristoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification. It has been used as a helper lipid for in vitro and in vivo gene transfer, and it has been shown to have some anticancer activity.
Application
MAPCHO™-14 has been used as a supplement in extraction buffer (RIPA buffer).
Biochem/physiol Actions
Fos-choline-14 (N-tetradecylphosphocholine) is mainly used for solubilization and purification of proteins.
Packaging
20 mL Clear Glass Screw Cap Vial (850338P-1g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850338P-10g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line
Cook BL, et al.
Testing, 3(8), e2920-e2920 (2008)
Brian L Cook et al.
PloS one, 3(8), e2920-e2920 (2008-08-07)
In order to begin to study the structural and functional mechanisms of olfactory receptors, methods for milligram-scale purification are required. Here we demonstrate the production and expression of a synthetically engineered human olfactory receptor hOR17-4 gene in a stable tetracycline-inducible
Reinhard Zeisig et al.
Cancer gene therapy, 10(4), 302-311 (2003-04-08)
To improve liposomal gene transfer we investigated the influence of membrane-interacting alkylphospholipids (APLs) on gene transfer efficiency in vitro and in vivo using the LacZ reporter gene and the cytosine deaminase (CD) suicide gene. Liposomes were first optimized concerning the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 850338P-10G | 04061835230235 |
| 850338P-1G | 04061835230242 |