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Safety Information

850335C

Avanti

12:0 PC (DLPC)

1,2-dilauroyl-sn-glycero-3-phosphocholine, chloroform

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Synonym(s):
1,2-didodecanoyl-sn-glycero-3-phosphocholine; DLPC; PC(12:0/12:0)
Empirical Formula (Hill Notation):
C32H64NO8P
CAS Number:
18194-25-7
Molecular Weight:
621.83
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850335C-25mg)
pkg of 1 × 20 mL (850335C-500mg)
pkg of 2 × 4 mL (850335C-200mg)

manufacturer/tradename

Avanti Polar Lipids 850335C

concentration

10 mg/mL (850335C-25mg)
25 mg/mL (850335C-200mg)
25 mg/mL (850335C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m0/s1

InChI key

IJFVSSZAOYLHEE-PMERELPUSA-N

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
The mucosal layer of the colon has phosphatidylcholine (PC). PCs carry fatty acids in the sn-1 and sn-2 positions, that are covalently attached to a glycerol through ester bonds.

Application

12:0 PC (DLPC/1,2-dilauroyl-sn-glycero-3-phosphocholine) may be used as a standard to quantify phosphatidylcholine. It has also been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions.

Biochem/physiol Actions

Phosphatidylcholine (PC) has the ability to block the penetrance of bacteria by acting as a surfactant.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850335C-500mg)
5 mL Clear Glass Sealed Ampule (850335C-200mg)
5 mL Clear Glass Sealed Ampule (850335C-25mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comprehensive untargeted lipidomic analysis using core
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Journal of Chromatography A, 1440, 123-134 null
Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol, 6, 1849e-1849e null
Inflammatory Bowel Disease
Parian AM, et al.
Integrative Medicine, 501-516 null
Nhiem Tran et al.
The journal of physical chemistry letters, 9(12), 3397-3402 (2018-05-29)
The transition between the lyotropic liquid crystalline lamellar and the bicontinuous cubic mesophase drives multiple fundamental cellular processes involving changes in cell membrane topology, including endocytosis and membrane budding. While several theoretical models have been proposed to explain this dynamic
John P Kowalski et al.
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