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850320C

Avanti

09:0 PC

1,2-dinonanoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

PC(9:0/9:0)

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About This Item

Empirical Formula (Hill Notation):
C26H52NO8P
CAS Number:
27869-45-0
Molecular Weight:
537.67
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850320C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850320C

concentration

10 mg/mL (850320C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C26H52NO8P/c1-6-8-10-12-14-16-18-25(28)32-22-24(35-26(29)19-17-15-13-11-9-7-2)23-34-36(30,31)33-21-20-27(3,4)5/h24H,6-23H2,1-5H3/t24-/m1/s1

InChI key

CKGVBFQDYSPMSY-XMMPIXPASA-N

General description

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the membrane. The fatty acids in the sn-1 and sn-2 positions of PCs are covalently attached to a glycerol with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

09:0 PC (1,2-dinonanoyl-sn-glycero-3-phosphocholine) may be used:
  • as an internal standard for phospholipid extraction from renal tissues using liquid chromatography coupled to electrospray ionization tandem mass spectrometry
  • as a supplement in sample mixture as internal standard for liquid-liquid extraction and to spike the samples in order to determine lipid extract from fibroblasts by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
  • an internal standard to spike frozen aliquots of plasma in liquid chromatography with tandem mass spectrometry (LC-MS-MS)

Biochem/physiol Actions

The physical properties of membranes can be modulated with the help of fatty acyl configuration of phosphatidylcholines (PCs). They serve as a major source for eicosanoids.

Packaging

5 mL Clear Glass Sealed Ampule (850320C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Regulatory Information

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Maria Philippova et al.
Free radical biology & medicine, 144, 167-175 (2019-05-30)
Circulating oxidized phospholipids are increasingly recognized as biomarkers of atherosclerosis. Clinical association studies have been mainly performed using an immune assay based on monoclonal antibody E06, which recognizes a variety of molecular species of oxidized phosphatidylcholine (OxPC) in lipoproteins, cell
Florian Gruber et al.
Journal of lipid research, 53(6), 1232-1242 (2012-03-15)
Oxidized phospholipids (OxPLs) are increasingly recognized as signaling mediators that are not only markers of oxidative stress but are also "makers" of pathology relevant to disease pathogenesis. Understanding the biological role of individual molecular species of OxPLs requires the knowledge
Zahra Solati et al.
PloS one, 13(4), e0195172-e0195172 (2018-04-24)
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury. Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for 45 min followed by
Keishi Kanno et al.
Biochimica et biophysica acta, 1771(6), 654-662 (2007-05-15)
Phosphatidylcholine transfer protein (PC-TP) is a highly specific soluble lipid binding protein that transfers phosphatidylcholine between membranes in vitro. PC-TP is a member of the steroidogenic acute regulatory protein-related transfer (START) domain superfamily. Although its biochemical properties and structure are

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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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