850311P
Avanti
DOCP
Avanti Polar Lipids 850311P, powder
Sign Into View Organizational & Contract Pricing
All Photos(2)
Synonym(s):
2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate
Empirical Formula (Hill Notation):
C43H82NO8P
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 mg (850311P-100mg)
pkg of 1 × 200 mg (850311P-200mg)
manufacturer/tradename
Avanti Polar Lipids 850311P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H]C(C[N+](C)(CCOP([O-])(O)=O)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
General description
Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.
Application
DOCP is suitable for use in preparation of
- supported phospholipid monolayer for human C-reactive protein binding studies
- large unilamellar vesicles (LUVs)
- liposomes for uptake studies in human astrocytes
Packaging
20 mL Clear Glass Screw Cap Vial (850311P-200mg)
5 mL Amber Glass Screw Cap Vial (850311P-100mg)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Sulfocerebrosides upregulate liposome uptake in human astrocytes without inducing a proinflammatory response
Suesca , et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 83(7), 627-635 (2013)
Specific binding of human C-reactive protein towards supported monolayers of binary and engineered phospholipids
Goda T and Miyahara Y
Colloids and Surfaces. B, Biointerfaces, 161, 662-669 (2018)
Inorganic cadmium affects the fluidity and size of phospholipid based liposomes
Kerek EM and Prenner EJ
Biochimica et Biophysica Acta - Biomembranes, 1858(12), 3169-3181 (2016)
Yibo Liu et al.
Langmuir : the ACS journal of surfaces and colloids, 34(32), 9337-9348 (2018-03-13)
Phospholipids are a major component of the cell membrane. In most natural phospholipids, the phosphate acts as a bridge, connecting the other portion of the polar headgroup with the hydrophobic tails. Such bridging phosphate is chemically quite inert. Synthetic lipids
Emily K Perttu et al.
Journal of the American Chemical Society, 134(10), 4485-4488 (2012-03-01)
Zwitterionic inverse-phosphocholine (iPC) lipids contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Neutral iPC
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service