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850310P

Avanti

DOBAQ

Avanti Polar Lipids 850310P, powder

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Synonym(s):
N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium
Empirical Formula (Hill Notation):
C49H83NO6
CAS Number:
Molecular Weight:
782.19
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850310P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850310P

lipid type

cationic lipids
headgroup modified lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(CCCCCCC/C=C\CCCCCCCC)OCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)CC1=CC=C(C([O-])=O)C=C1

General description

DOBAQ is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. It is a pH-sensitive lipid.

Biochem/physiol Actions

N-(4-carboxybenzyl)-N,N-dimethyl2,3-bis(oleoyloxy)propan-1-aminium/DOBAQ displays pH-dependent ionization.

Packaging

5 mL Clear Glass Sealed Ampule (850310P-25mg)

Regulatory Information

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Certificates of Analysis (COA)

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Liposomes in Analytical Methodologies (2016)
Lipid nanoparticles for delivery of messenger RNA to the back of the eye
Patel S, et al.
J. Controlled Release, 303, 91-100 (2019)

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