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850303P

Avanti

04:0 PC

1,2-dibutyryl-sn-glycero-3-phosphocholine, powder

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Synonym(s):
PC(4:0/4:0)
Empirical Formula (Hill Notation):
C16H32NO8P
CAS Number:
3355-26-8
Molecular Weight:
397.40
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850303P-25mg)
pkg of 1 × 500 mg (850303P-500mg)

manufacturer/tradename

Avanti Polar Lipids 850303P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COC(CCC)=O)=O

InChI

1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1

InChI key

QIJYAMAPPUXBSC-CQSZACIVSA-N

General description

04:0 PC is a water soluble phophatidylcholine analogue. Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

04:0 PC is suitable for use to evaluate its ability to form reverse micelles. It is also suitable for use as a phospholipid substrate to study the substrate specificity of glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP).

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

30 mL Amber Wide Mouth Bottle with Screw Cap (850303P-500mg)
5 mL Clear Glass Sealed Ampule (850303P-25mg)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Integrative Medicine - E-Book (2017)
The Membranes of Cells (2016)
Role of reverse micelles on lipid oxidation in bulk oils: impact of phospholipids on antioxidant activity of alpha-tocopherol and Trolox
Chen B, et al.
Food & Function, 2(6), 302-309 (2011)
Characterization of glycerophosphoethanolamine ethanolaminephosphodiesterase from Streptomyces sanglieri
Mineta S, et al.
Journal of Bioscience and Bioengineering, 119(2), 123-130 (2015)
Mi-Kyung Oh et al.
Biochimica et biophysica acta, 1649(2), 146-153 (2003-07-25)
O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates (n=6, 8, and 10; CnPNC) were synthesized and characterized as inhibitors of phospholipase D (PLD) activity toward phosphatidylcholine presented as monomers, micelles, and bilayers. Detailed studies with recombinant Streptomyces chromofuscus PLD, a Ca(2+)-activated enzyme that does not show large
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