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850100P

Avanti

18:1 Lyso PI

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

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Synonym(s):
1-(9Z-octadecenoyl)-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt); PI(18:1(9Z)/0:0); 110720
Empirical Formula (Hill Notation):
C27H54NO12P
CAS Number:
1246298-13-4
Molecular Weight:
615.69
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850100P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850100P-500ug))

manufacturer/tradename

Avanti Polar Lipids 850100P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

General description

Phosphatidylinositol (PtdIns) is a structural phospholipid. PI is synthesized by mycobacteria and other bacterial genera in prokaryotes.

Application

18:1 Lyso PI is suitable for use to quantify the fatty acids, lysophospholipids (LPLs), and phospholipids (PLs) and LPAs in gintonin-enriched fraction (GEF) by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem/physiol Actions

Phosphatidylinositol (PI) participates in polyphosphoinositide turnover. It can be used as a substrate to produce several molecules, that can modulate various cellular functions. In eukaryotes, phosphatidylinositol (PI)-based lipids (phosphoinositides) plays a key role in intracellular signalling. It is also involved in the anchoring of glycosylphosphatidylinositol-linked proteins to the membrane.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850100P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850100P-500ug)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phosphatidylinositol 4-Kinase from Bovine Brain
Methods in Neurosciences, 18, 93-99 (1993)
Phosphatidylinositol Turnover and Receptors
reference module in biomedical sciences (2016)
Bioactive lipids in gintonin-enriched fraction from ginseng
Cho HJ, et al.
Journal of ginseng research (2017)
Structural basis for phosphatidylinositol-phosphate biosynthesis
Clarke OB, et al.
Nature Communications, 6, 8505-8505 (2015)
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple

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