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841138P

Avanti

Egg PG

Avanti Research™ - A Croda Brand

Synonym(s):

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-sn-1-glycerol sodium salt, L-α-phosphatidylglycerol (Egg, Chicken) (sodium salt)

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About This Item

CAS Number:
383907-64-0
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (841138P-200mg)
pkg of 5 × 100 mg (841138P-500mg)
pkg of 1 × 25 mg (841138P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

General description

Phosphatidylglycerol (PG) is one of the major phospholipids in food and biological tissues. PG, structurally has two acyl chains esterified to a glycerol, which in turn is bonded to a headgroup structure that has phosphate and carries negative charge. PG is abundant in bacterial membranes and present in lower amounts in mammalian membranes. It is abundant in lung surfactant. PG is synthesized from cytidine phosphate-diacylglycerol (CDP-DAG).

Application

Egg PG has been used as anionic phospholipid substrate in serial protein misfolding cyclic amplification (sPMCA) reaction. It is also suitable for use in the preparation of large unilamellar vesicles (LUVs) and as a standard for liquid chromatography-mass spectrometric analysis (LC-MS).

Biochem/physiol Actions

Phosphatidylglycerol (PG) is an indicator of fetal lung maturity. It is a precursor for cardiolipin in animals. In plants, PG is present in thylakoid membranes and plays a central role in photosynthesis.

Packaging

5 mL Clear Glass Sealed Ampule (841138P-200mg)
5 mL Clear Glass Sealed Ampule (841138P-25mg)
5 mL Clear Glass Sealed Ampule (841138P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Deleault NR, et al.
Proceedings of the National Academy of Sciences, 109(22), 8546-8551 (2012)
Phosphatidylglycerol in amniotic fluid: comparison of an ?ultrasensitive? immunologic assay with TLC and enzymatic assay
Eisenbrey AB, et al.
American Journal of Bioscience, 91(3), 293-297 (1989)
The
An Introduction to Biological Membranes: Composition, Structure and Function, 91(3) (2016)
The
The Membranes of Cells, 911(3) (2016)
Célia Jacoberger-Foissac et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 152, 348-357 (2020-06-02)
Liposomes are powerful tools for the optimization of peptides and adjuvant composition in cancer vaccines. Here, we take advantage of a liposomal platform versatility to develop three vaccine candidates associating a peptide from HA influenza virus protein as CD4 epitope
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