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841138C

Avanti

Egg PG

Avanti Polar Lipids

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Synonym(s):
L-α-phosphatidylglycerol (Egg, Chicken) (sodium salt)
CAS Number:
383907-64-0
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (841138C-25mg)
pkg of 2 × 4 mL (841138C-200mg)
pkg of 5 × 4 mL (841138C-500mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (841138C-25mg)
25 mg/mL (841138C-200mg)
25 mg/mL (841138C-500mg)

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

General description

Phosphatidylglycerol (PG) is one of the major phospholipids in food and biological tissues. PG is the anionic phospholipid in the membranes of Staphylococcus sp. and Escherichia coli. PG is present in low amounts in mammalian membranes. Structurally, PG has two acyl chains esterified to a glycerol, bonded to a headgroup structure that has phosphate and carries negative charge. PG is synthesized from cytidine phosphate-diacylglycerol (CDP-DAG).

Application

Egg PG has been used:
  • as a phospholipid to test the binding ability of SEIPIN, an integral membrane protein of endoplasmic recticulum
  • as a standard for photodynamic treatment
  • as a standard for the identification of phospholipids by thin layer chromatography and electrospray ionization-mass spectra (ESI-MS)

Biochem/physiol Actions

Phosphatidylglycerol (PG) is present in amniotic fluid and indicates fetal lung maturity. It functions as a precursor for cardiolipin in animals. In plants, PG is present in thylakoid membranes and plays a central role in photosynthesis.

Packaging

5 mL Clear Glass Sealed Ampule (841138C-200mg)
5 mL Clear Glass Sealed Ampule (841138C-25mg)
5 mL Clear Glass Sealed Ampule (841138C-500mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Photodynamic oxidation of Escherichia coli membrane phospholipids: new insights based on lipidomics
Alves E, et al.
Rapid Communications in Mass Spectrometry, 27(23), 2717-2728 (2013)
The
The Membranes of Cells, 27(23) (2016)
The
An Introduction to Biological Membranes: Composition, Structure and Function, 91(3) (2016)
Validation of an LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues
Xiong Y, et al.
Journal of Chromatography. B, Biomedical Applications, 911, 170-179 (2012)
Célia Jacoberger-Foissac et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 152, 348-357 (2020-06-02)
Liposomes are powerful tools for the optimization of peptides and adjuvant composition in cancer vaccines. Here, we take advantage of a liposomal platform versatility to develop three vaccine candidates associating a peptide from HA influenza virus protein as CD4 epitope
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