841118P
Avanti
Egg Trans PE
L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken), powder
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Synonym(s):
L-a-Phosphatidylethanolamine Transphosphatidylated (prepared from Egg PC)
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (841118P-25mg)
manufacturer/tradename
Avanti Polar Lipids 841118P
lipid type
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O
General description
Phosphatidylethanolamine (PE) is a phospholipid found in all living organisms. The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group. The egg yolk contains high levels of unsaturated PE which accounts to 83.10%.
Application
Egg Trans PE is suitable for use:
- in the preparation of zwitterionic liposome for binding assay
- as a component in optimized theranostic nanoemulsion (NE) formulations
- in the preparation of large unilamellar vesicles (LUVs) for detecting the leakage of intraliposomal carboxyfluorescein caused by anthraquinones
Biochem/physiol Actions
Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation. Egg yolk PE has high radical scavenging activity owing to antioxidant potential.
Packaging
5 mL Clear Glass Sealed Ampule (841118P-25mg)
Certificates of Analysis (COA)
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The
The Membranes of Cells, 22(3) (2016)
Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein
Harrington JM, et al.
Journal of biological and chemical chronicles, 284(20), 13505-13512 (2009)
Niravkumar R Patel et al.
Cancer biology & therapy, 19(7), 554-564 (2018-05-09)
Ovarian cancer ranks fifth in cancer related deaths for women in USA. The high mortality rate associated with ovarian cancer is due to diagnosis at later stages of disease and the high recurrence rate of 60-80%. Recurrent ovarian cancers are
In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers
Patel NR, et al.
Cancer Biochemistry Biophysics, 19(7), 554-564 (2018)
Egg Yolk Phosphatidylethanolamine: Extraction Optimization, Antioxidative Activity, and Molecular Structure Profiling
Sun N, et al.
Journal of Food Science, 84(5), 1002-1011 (2019)
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