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840886C

Avanti

20:4 PA

1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt), chloroform

Synonym(s):

1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate (sodium salt); DAPA; PA(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))

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About This Item

Empirical Formula (Hill Notation):
C43H68O8PNa
CAS Number:
474943-33-4
Molecular Weight:
766.96
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840886C-25mg)
pkg of 2 × 4 mL (840886C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840886C

concentration

10 mg/mL (840886C-25mg)
25 mg/mL (840886C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[Na+]

InChI

1S/C43H69O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-42(44)49-39-41(40-50-52(46,47)48)51-43(45)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h11-14,17-20,23-26,29-32,41H,3-10,15-16,21-22,27-28,33-40H2,1-2H3,(H2,46,47,48);/q;+1/p-1/b13-11-,14-12-,19-17-,20-18-,25-23-,26-24-,31-29-,32-30-;/t41-;/m1./s1

InChI key

FDDKKAHLSUVCLC-QHEFBXHFSA-M

General description

Phosphatidic acid (PA) is a precursor of lysophosphatidic acid (LPA) and is present in leafy vegetables. 20:4 PA or 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt) is a sodium salt of phosphatidic acid, with substitution of two chains of arachidonic acid at the sn-1 and sn-2 positions, in the glycerol backbone.

Application

20:4 PA or 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt) has been used as a supplement in mouse chow to see changes in small intestine gene expression.

Packaging

5 mL Clear Glass Sealed Ampule (840886C-200mg)
5 mL Clear Glass Sealed Ampule (840886C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mohamad Navab et al.
Journal of lipid research, 54(12), 3403-3418 (2013-10-03)
We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR⁻/⁻) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but

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