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840475P

Avanti

18:1 (Δ9-Cis) PG

Avanti Polar Lipids

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Synonym(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))
Empirical Formula (Hill Notation):
C42H78O10PNa
CAS Number:
Molecular Weight:
797.03
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (840475P-1g)
pkg of 2 × 100 mg (840475P-200mg)
pkg of 5 × 100 mg (840475P-500mg)
pkg of 1 × 25 mg (840475P-25mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.

Application

18:1 (Δ9-Cis) PG has been used:
  • in the preparation of giant unilamellar vesicle (GUV)
  • in the preparation 200 nm large unilamellar vesicles (LUV)
  • as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840475P-200mg)
5 mL Clear Glass Sealed Ampule (840475P-25mg)
5 mL Clear Glass Sealed Ampule (840475P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (840475P-1g)

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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