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840434P

Avanti

10:0 PG

1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder

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Synonym(s):
PG(10:0/10:0)
Empirical Formula (Hill Notation):
C26H50O10PNa
CAS Number:
322647-25-6
Molecular Weight:
576.63
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (840434P-25mg)
pkg of 1 × 500 mg (840434P-500mg)

manufacturer/tradename

Avanti Polar Lipids 840434P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O.[Na+]

InChI

1S/C26H51O10P.Na/c1-3-5-7-9-11-13-15-17-25(29)33-21-24(22-35-37(31,32)34-20-23(28)19-27)36-26(30)18-16-14-12-10-8-6-4-2;/h23-24,27-28H,3-22H2,1-2H3,(H,31,32);/q;+1/p-1/t23?,24-;/m1./s1

InChI key

WOGMIDKKARMDEU-RETUOTIWSA-M

General description

Phosphatidylglycerol (PG) is one of the important lipid, found in the membranes of bacteria. But in mammals, PG accounts for only 1–2 mol% of phospholipids. This lipid is abundantly present in the lung surfactant. thus pointing to an important role therein.

Application

10:0 PG (1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used as a component in the liposomes, labeled with β-pyrene-C10-PG. It may also be used in the preparation of small unilamellar vesicle (SUV) liposomes.

Biochem/physiol Actions

Phosphatidylglycerol (PG) serves as an indicator of lung maturity in fetus.

Packaging

30 mL Amber Wide Mouth Bottle with Screw Cap (840434P-500mg)
5 mL Clear Glass Sealed Ampule (840434P-25mg)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alison H Dewald et al.
Biophysical journal, 100(9), 2131-2140 (2011-05-05)
The spontaneous folding of two Neisseria outer membrane proteins, opacity-associated (Opa)(60) and Opa(50) into lipid vesicles was investigated by systematically varying bulk and membrane properties. Centrifugal fractionation coupled with sodium dodecyl sulfate polyacrylamide gel electrophoresis mobility assays enabled the discrimination
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Camilo F Muñoz et al.
Frontiers in plant science, 10, 1573-1573 (2019-12-19)
Microalgal lipids are promising feedstocks for food and biofuels. Since lipid production by microalgae is not yet economically feasible, genetic engineering is becoming a promising strategy to achieve higher lipid accumulation and productivities. Enzymes involved in the Kennedy pathway such
A B Eisenbrey et al.
American journal of clinical pathology, 91(3), 293-297 (1989-03-01)
Phosphatidylglycerol (PG) in amniotic fluid is recognized as a good indicator of fetal lung maturity and is unaffected by moderate amounts of blood or meconium contamination. A rapid immunologic agglutination assay, Ultrasensitive AmnioStat-FLM (FLM), was compared with two-dimensional thin-layer chromatography
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Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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