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840434C

Avanti

10:0 PG

1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

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Synonym(s):
PG(10:0/10:0)
Empirical Formula (Hill Notation):
C26H50O10PNa
CAS Number:
322647-25-6
Molecular Weight:
576.63
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840434C-25mg)
pkg of 1 × 20 mL (840434C-500mg)

manufacturer/tradename

Avanti Polar Lipids 840434C

concentration

10 mg/mL (840434C-25mg)
25 mg/mL (840434C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C26H51O10P.Na/c1-3-5-7-9-11-13-15-17-25(29)33-21-24(22-35-37(31,32)34-20-23(28)19-27)36-26(30)18-16-14-12-10-8-6-4-2;/h23-24,27-28H,3-22H2,1-2H3,(H,31,32);/q;+1/p-1/t23?,24-;/m1./s1

InChI key

WOGMIDKKARMDEU-RETUOTIWSA-M

General description

Phosphatidylglycerol (PG), an anionic lipid is present in the membranes of mammals. It accounts for 1–2% of the total phospholipids.

Application

10:0 PG (1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used as a component in the liposomes, labeled with β-pyrene-C10-PG. It may also be used as a lipid standard to compare accurate lipid quantification with deuterated standard lipids using electrospray ionization (ESI).

Biochem/physiol Actions

In cyanobacteria and plants, phosphatidylglycerol (PG) plays a key role in the formation and activities of thylakoid membranes. Absence of PG can bring a change in the function of photosystem (PS) I and PSII reaction centers (RCs).

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840434C-500mg)
5 mL Clear Glass Sealed Ampule (840434C-25mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Information

危险化学品
易制毒化学品（2类）

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Membrane Polar Lipids
An Introduction to Biological Membranes (2016)
Hajnalka Laczkó-Dobos et al.
Biochimica et biophysica acta, 1777(9), 1184-1194 (2008-07-01)
To analyze the role of phosphatidylglycerol (PG) in photosynthetic membranes of cyanobacteria we used two mutants of Synechocystis sp. PCC6803: the PAL mutant which has no phycobilisomes and shows a high PSII/PSI ratio, and a mutant derived from it by
Camilo F Muñoz et al.
Frontiers in plant science, 10, 1573-1573 (2019-12-19)
Microalgal lipids are promising feedstocks for food and biofuels. Since lipid production by microalgae is not yet economically feasible, genetic engineering is becoming a promising strategy to achieve higher lipid accumulation and productivities. Enzymes involved in the Kennedy pathway such
Tommy Hofmann et al.
Chemistry and physics of lipids, 223, 104782-104782 (2019-06-10)
In recent years, lipid quantification gained importance. In most cases, this is achieved by spiking the lipid mixture with deuterated standard lipids or lipid analogues that differ in chain length when compared with the natural lipid components. Usually, conventional ESI
Brianna M Abbott et al.
Biochimica et biophysica acta. Biomembranes, 1860(5), 1187-1192 (2018-02-13)
Experiments investigating the adsorption and desorption of cytochrome c onto and from liposomes containing 50 mol% 1,2-diacylphosphatidylglycerol lipids [10:0, 12:0, 14:0, 16:0, 18:1(Δ9 cis)] with 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) in pH 7.4 buffered solutions of low to moderate ionic strength are reported. Fluorescence experiments

Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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