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840420P

Avanti

18:1 Phosphatidylmethanol

1,2-dioleoyl-sn-glycero-3-phosphomethanol (sodium salt), powder

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Synonym(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphomethanol (sodium salt)
Empirical Formula (Hill Notation):
C40H74O8PNa
CAS Number:
151379-99-6
Molecular Weight:
736.97
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (840420P-25mg)

manufacturer/tradename

Avanti Polar Lipids 840420P

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C40H75O8P.Na/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-39(41)46-36-38(37-47-49(43,44)45-3)48-40(42)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2;/h18-21,38H,4-17,22-37H2,1-3H3,(H,43,44);/q;+1/p-1/b20-18-,21-19-;/t38-;/m1./s1

InChI key

VZVXMZAFOPVENO-MDTXTNHHSA-M

General description

18:1 Phosphatidylmethanol (1,2-dioleoyl-sn-glycero-3-phosphomethanol) is a phospholipid which carries an anionic head group. It is categorized as an alkyl phosphate under lipd headgroup modified lipids.

Application

18:1 Phosphatidylmethanol (1,2-dioleoyl-sn-glycero-3-phosphomethanol) may be used in unilamellar vesicles for fluorescence quenching vesicle binding assay and as an internal standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) analysis for the quantification of phosphatidylethanols (PEths) in whole blood, venous/capillary-dried blood spots (V-DBS and C-DBS).

Packaging

5 mL Clear Glass Sealed Ampule (840420P-25mg)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Brian Jeppesen et al.
The Journal of biological chemistry, 283(10), 6126-6135 (2008-01-05)
Annexin V binds to membranes with very high affinity, but the factors responsible remain to be quantitatively elucidated. Analysis by isothermal microcalorimetry and calcium titration under conditions of low membrane occupancy showed that there was a strongly positive entropy change
Natalie Kummer et al.
Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)
Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and

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