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840053C

Avanti

Brain PC

Avanti Polar Lipids 840053C

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Synonym(s):
L-α-phosphatidylcholine (Brain, Porcine)
CAS Number:
383907-52-6
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840053C-25mg)
pkg of 2 × 4 mL (840053C-200mg)

manufacturer/tradename

Avanti Polar Lipids 840053C

concentration

10 mg/mL (840053C-25mg)
25 mg/mL (840053C-200mg)

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

General description

Phosphatidylcholine (PC) is a predominant glycerophospholipid in eukaryotes. Brain PC predominantly contains PC 16:0/16:0 and PC 16:0/18:1.

Application

Brain PC is suitable for use in the preparation of lipid mixture for microplate (enzyme linked immunosorbent assay (ELISA))-based recognition of glycolipid-protein interaction assay and liposomes for co-sedimentation assay. Brain PC has been used in the preparation of liposomes for integration of receptors.

Biochem/physiol Actions

Phosphatidylcholine (PC) is the major source of second messengers and lipid mediators. It is intermediate in the synthesis of other phospholipids.

Packaging

5 mL Clear Glass Sealed Ampule (840053C-200mg)
5 mL Clear Glass Sealed Ampule (840053C-25mg)

also commonly purchased with this product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Choline, Phospholipids, Health, and Disease (1998)
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei.
Farine L, et al.
Scientific Reports, 5(5), 16787-16787 (2015)
Geoffrey P Noble et al.
Biochemistry, 54(5), 1180-1187 (2015-01-15)
Misfolding of the prion protein (PrP) plays a central role in the pathogenesis of infectious, sporadic, and inherited prion diseases. Here we use a chemically defined prion propagation system to study misfolding of the pathogenic PrP mutant D177N in vitro.
Sanchaita Das et al.
Structure (London, England : 1993), 27(12), 1782-1797 (2019-10-12)
Membrane dynamic processes require Arf GTPase activation by guanine nucleotide exchange factors (GEFs) with a Sec7 domain. Cytohesin family Arf GEFs function in signaling and cell migration through Arf GTPase activation on the plasma membrane and endosomes. In this study
Determination of glycolipid-protein interaction specificity.
Lopez PHH and Schnaar RL
Methods in Enzymology, 417, 205-220 (2006)
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