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840044P

Avanti

Soy PI

Avanti Polar Lipids

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Synonym(s):
L-α-phosphatidylinositol (Soy) (sodium salt)
CAS Number:
383907-36-6
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840044P-10mg)
pkg of 2 × 100 mg (840044P-200mg)
pkg of 1 × 25 mg (840044P-25mg)
pkg of 1 × 50 mg (840044P-50mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP([O-])(OC[C@@]([H])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O.[Na+]

InChI

1S/C43H79O13P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(45)55-35(34-54-57(51,52)56-43-41(49)39(47)38(46)40(48)42(43)50)33-53-36(44)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35,38-43,46-50H,3-10,12,14-16,19-34H2,1-2H3,(H,51,52);/q;+1/p-1/b13-11-,18-17-;/t35-,38?,39-,40?,41?,42?,43-;/m1./s1

InChI key

DCDQYHYLAGWAPO-UQZYTPKFSA-M

General description

L-α-phosphatidylinositol (Soy) is a negatively charged, naturally occurring glycerophospholipid with an inositol ring. It is found in biological membranes, which takes part in scaffolding, cellular compartmentalization, and signal transduction.

Application

Soy PI has been used in the preparation of liposomes.

Biochem/physiol Actions

L-α-phosphatidylinositol (Soy) plays a key role as a cellular mediator during signal transduction processes. It is used to design therapeutic delivery vehicle for drug delivery. Soy PI also contributes to the regulation of cholesterol metabolism.

Packaging

5 mL Clear Glass Sealed Ampule (840044P-10mg)
5 mL Clear Glass Sealed Ampule (840044P-200mg)
5 mL Clear Glass Sealed Ampule (840044P-25mg)
5 mL Clear Glass Sealed Ampule (840044P-50mg)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phospholipids as cardiovascular therapeutics
Pandey NR and Sparks DL
Current Opinion in Investigational Drugs, 9(3), 281-285 (2008)
Aaron Peng et al.
Chemistry and physics of lipids, 165(1), 15-22 (2011-10-26)
Liposomes consisted of phosphatidylinositol (PI) and phosphatidylcholine (PC) have been utilized as delivery vehicle for drugs and proteins. In the present work, we studied the effect of soy PI on physical properties of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes such as phase state
Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.
Sevova ES, et al.
The Journal of Biological Chemistry, 285(27), 20580-20587 (2010)
Yoshiko Uchiyama et al.
Brain research, 1151, 46-54 (2007-04-06)
Membrane composition serves to identify intracellular compartments, signal cell death, as well as to alter a cell's electrical and physical properties. Here we use amperometry to show that supplementation with the phospholipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), sphingomyelin (SM), and phosphatidylserine
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
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