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840034C

Avanti

16:0-18:1 PS (POPS)

Avanti Polar Lipids

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Synonym(s):
1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS; PS(16:0/18:1(9Z)); 110669
Empirical Formula (Hill Notation):
C40H75NO10PNa
CAS Number:
321863-21-2
Molecular Weight:
783.99
UNSPSC Code:
12352211
NACRES:
NA.25

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (840034C-10mg)
pkg of 1 × 2.5 mL (840034C-25mg)
pkg of 2 × 4 mL (840034C-200mg)
pkg of 5 × 4 mL (840034C-500mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (840034C-10mg)
10 mg/mL (840034C-25mg)
25 mg/mL (840034C-200mg)
25 mg/mL (840034C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Packaging

5 mL Clear Glass Sealed Ampule (840034C-10mg)
5 mL Clear Glass Sealed Ampule (840034C-200mg)
5 mL Clear Glass Sealed Ampule (840034C-25mg)
5 mL Clear Glass Sealed Ampule (840034C-500mg)

also commonly purchased with this product

Product No.
Description
Pricing

C8667

Cholesterol, Sigma Grade, ≥99%

700000P

Cholesterol (ovine), Avanti Polar Lipids

710335C

18:1 Cardiolipin, Avanti Polar Lipids

810150C

18:1 Liss Rhod PE, Avanti Polar Lipids

840033P

14:0 PS, Avanti Polar Lipids

840035C

18:1 PS (DOPS), Avanti Polar Lipids

840457C

16:0-18:1 PG, Avanti Polar Lipids

840857C

16:0-18:1 PA, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt), chloroform

850150P

18:1 PI(3)P, Avanti Polar Lipids

850155P

18:1 PI(4,5)P2, Avanti Polar Lipids

850355P

16:0 PC (DPPC), Avanti Polar Lipids

850365C

18:0 PC (DSPC), Avanti Polar Lipids

850375C

18:1 (Δ9-Cis) PC (DOPC), Avanti Polar Lipids

850457C

16:0-18:1 PC, Avanti Polar Lipids

850457P

16:0-18:1 PC, Avanti Polar Lipids

850705P

16:0 PE, Avanti Polar Lipids

850725C

18:1 (Δ9-Cis) PE (DOPE), Avanti Polar Lipids

850757C

16:0-18:1 PE, Avanti Polar Lipids

840046X

Brain PI(4,5)P2, Avanti Polar Lipids

840051C

Egg PC, Avanti Polar Lipids

860061C

Egg SM, Avanti Polar Lipids

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Josef Melcr et al.
Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
R J Perrin et al.
The Journal of biological chemistry, 275(44), 34393-34398 (2000-08-23)
alpha-Synuclein has been centrally implicated in neurodegenerative disease, and a normal function in developmental synaptic plasticity has been suggested by studies in songbirds. A variety of observations suggest the protein partitions between membrane and cytosol, a behavior apparently conferred by
Carina Drechsler et al.
Biophysical journal, 115(8), 1509-1517 (2018-09-30)
Lipid asymmetries between the outer and inner leaflet of the lipid bilayer exist in nearly all biological membranes. Although living cells spend great effort to adjust and maintain these asymmetries, little is known about the biophysical phenomena within asymmetric membranes
Maria J Sarmento et al.
Langmuir : the ACS journal of surfaces and colloids, 33(43), 12463-12477 (2017-09-30)
Although the evidence for the presence of functionally important nanosized phosphorylated phosphoinositide (PIP)-rich domains within cellular membranes has accumulated, very limited information is available regarding the structural determinants for compartmentalization of these phospholipids. Here, we used a combination of fluorescence
Dorotea Fracchiolla et al.
eLife, 5 (2016-11-24)
Selective autophagy is mediated by cargo receptors that link the cargo to the isolation membrane via interactions with Atg8 proteins. Atg8 proteins are localized to the membrane in an ubiquitin-like conjugation reaction, but how this conjugation is coupled to the
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