810890P
Avanti
Fluorescent DOTAP
1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-3-trimethylammonium propane (chloride salt), powder
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All Photos(2)
Synonym(s):
18:1-06:0 NBD DOTAP
Empirical Formula (Hill Notation):
C36H60ClN5O7
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 50 μg (810890P-50ug)
manufacturer/tradename
Avanti Polar Lipids 810890P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]
General description
N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium (DOTAP) is a cationic lipid, which forms strong complexes with DNA. It aids the cellular delivery of RNA and DNA. DOTAP acts as a transfection agent.
Application
Fluorescent DOTAP has been used for the preparation of liposomes loaded with gold and verteporfin (VP).
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810890P-50ug)
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Neurons: Methods and Applications for the Cell Biologist (2003)
Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
Deng W, et al.
Nature Communications, 9(1), 2713-2713 (2018)
Phospholipid-cationic lipid interactions: influences on membrane and vesicle properties
Campbell RB, et al.
Biochimica et Biophysica Acta - Biomembranes, 1512(1), 27-39 (2001)
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