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810606C

Avanti

16:0 Tempo PC

1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline, chloroform

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Synonym(s):
Tempo-PCSL
Empirical Formula (Hill Notation):
C48H94N2O9P
CAS Number:
63658-52-6
Molecular Weight:
874.24
UNSPSC Code:
41141825
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810606C-1mg)

manufacturer/tradename

Avanti Polar Lipids 810606C

concentration

1 mg/mL (810606C-1mg)

lipid type

phospholipids
ESR probes

shipped in

dry ice

storage temp.

−20°C

General description

1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline serves as a spin label which is generally used to analyse the microenvironments in lipid membranes. This includes the viscosity and polarity.

Application

16:0 Tempo PC has been used in spin labelling:
  • to analyze the dependence of the packing and polarity of DLPC (1,2-dilauroyl-sn-glycero-3-phosphocholine) bilayers with temperature
  • of phospholipids for the measuring paramagnetic relaxation rates
  • lipids to obtain the depth calibration curve

Packaging

5 mL Clear Glass Sealed Ampule (810606C-1mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Information

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Interaction of local anesthetics with lipid bilayers investigated by 1H MAS NMR spectroscopy
Weizenmann N, et al.
Biochimica et Biophysica Acta - Biomembranes, 1818(12), 3010-3018 (2012)
Membrane-anchoring and charge effects in the interaction of myelin basic protein with lipid bilayers studied by site-directed spin labeling
Bates IR, et al.
The Journal of Biological Chemistry, 278(31), 29041-29047 (2003)
Laurdan in fluid bilayers: position and structural sensitivity
De Vequi-Suplicy, et al.
Journal of Fluorescence, 16(3), 431-439 (2006)
Diego E Sastre et al.
The Journal of biological chemistry, 295(7), 2136-2147 (2019-12-05)
PlsX plays a central role in the coordination of fatty acid and phospholipid biosynthesis in Gram-positive bacteria. PlsX is a peripheral membrane acyltransferase that catalyzes the conversion of acyl-ACP to acyl-phosphate, which is in turn utilized by the polytopic membrane

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