810509P
Avanti
18:1 Dabsyl PE
Avanti Polar Lipids 810509P, powder
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Synonym(s):
1,2-dioleyl-sn-glycero-3-phosphoethanolamine-N-(dabsyl) (ammonium salt)
Empirical Formula (Hill Notation):
C55H94N5O10PS
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (810509P-5mg)
manufacturer/tradename
Avanti Polar Lipids 810509P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphoethanolamine is a precursor to phosphatidylcholine and phosphatidylethanolamine. Dabsyl-PE carries contains a dark quencher in the headgroup.
Biochem/physiol Actions
Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and vascular endothelial growth factor receptor 1 (VEGFR1). Dabsyl-PE has the ability to quench superfolder green fluorescent protein, (SfGFP).
Packaging
5 mL Amber Glass Screw Cap Vial (810509P-5mg)
WGK
WGK 3
Regulatory Information
新产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Synthetic phosphoethanolamine: the state of the art of scientific production
Anastacio L de B, et al.
Brazilian Journal of Pharmaceutical Sciences , 53(4) (2017)
Hyunjin Kim et al.
Journal of lipid research, 54(12), 3531-3538 (2013-09-06)
Membrane-protein interaction plays key roles in a wide variety of biological processes. Although various methods have been employed to measure membrane binding of soluble proteins, a robust high-throughput assay that is universally applicable to all proteins is lacking at present.
Gokul Raghunath et al.
Langmuir : the ACS journal of surfaces and colloids, 35(38), 12550-12561 (2019-08-31)
Nickel-chelating lipids offer a convenient platform for reversible immobilization of histidine-tagged proteins to liposome surfaces. This interaction recently found utility as a model system for studying membrane remodeling triggered by protein crowding. Despite its wide array of utility, the molecular
Rosie Dawaliby et al.
The Journal of biological chemistry, 291(7), 3658-3667 (2015-12-15)
Adequate membrane fluidity is required for a variety of key cellular processes and in particular for proper function of membrane proteins. In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid desaturation and cholesterol, although some
Noam Pondé et al.
Ecancermedicalscience, 10, 681-681 (2016-12-03)
The use of unproven forms of therapy in cancer treatment is very common. In Brazil, the distribution by researchers to patients of an investigational agent called phophoethanolamine (PHOS) has led to a widely publicized scientific scandal. PHOS is a precursor
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