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810330C

Avanti

18:1 Dansyl PE

Avanti Polar Lipids 810330C

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Synonym(s):
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(5-dimethylamino-1-naphthalenesulfonyl) (ammonium salt)
Empirical Formula (Hill Notation):
C53H92N3O10PS
CAS Number:
474942-79-5
Molecular Weight:
994.35
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810330C-1mg)
pkg of 5 × 1 mL (810330C-5mg)

manufacturer/tradename

Avanti Polar Lipids 810330C

concentration

1 mg/mL (810330C-1mg)
1 mg/mL (810330C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 Dansyl PE is a hygroscopic, light sensitive lipid.

Application

18:1 Dansyl PE has been used in unilamellar liposome preparation. It may be used to incorporate into liposomes as the fluorescence energy transfer (FRET) acceptor. It may also be used as a component in Golgi-like acceptor liposomes for lipid transfer assay.

Biochem/physiol Actions

Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).

Packaging

5 mL Amber Glass Screw Cap Vial (810330C-1mg)
5 mL Amber Glass Screw Cap Vial (810330C-5mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Biochemical and biophysical research communications, 521(3), 732-738 (2019-11-11)
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Phosphoethanolamine and the danger of unproven drugs
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Synthetic phosphoethanolamine: the state of the art of scientific production
Anastacio L de B, et al.
Brazilian Journal of Pharmaceutical Sciences , 53(4), 3658-3667 (2017)
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