Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

810286C

Avanti

TopFluor® Cardiolipin

1,1′,2,2′-tetraoleoyl cardiolipin[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt) TopFluor® Cardiolipin, chloroform

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
1′,3′-bis[1,2-dioleoyl-sn-glycero-3-phospho]-2′-[4-(dipyrrometheneboron difluoride) butanoyl]-sn-glycerol (ammonium salt); TopFluor-CL
Empirical Formula (Hill Notation):
C98H175BF2N4O18P2
CAS Number:
2260795-91-1
Molecular Weight:
1808.21
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810286C-100ug)
pkg of 1 × 1 mL (810286C-500ug)

manufacturer/tradename

Avanti Polar Lipids 810286C

concentration

0.1 mg/mL (810286C-100ug)
0.5 mg/mL (810286C-500ug)

shipped in

dry ice

storage temp.

−20°C

General description

Cardiolipin, a unique phospholipid is present and synthesised in the inner mitochondrial membrane.
TopFluor® cardiolipin is a fluorescent analog of the bioactive phospholipid, cardiolipin.

Biochem/physiol Actions

Cardiolipin is very much essential for the functional activity of several inner mitochondrial membrane proteins, like respiratory chain complexes. It participates in mitochondrial oxidative phosphorylation. It is also essential for proper functioning and structure of the inner mitochondrial membrane (IMM).

Packaging

5 mL Amber Glass Screw Cap Vial (810286C-100ug)
5 mL Amber Glass Screw Cap Vial (810286C-500ug)

Legal Information

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Regulatory Information

危险化学品
易制毒化学品（2类）

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Clyde A Daly et al.
Langmuir : the ACS journal of surfaces and colloids, 36(18), 5030-5039 (2020-04-18)
The composition, orientation, and conformation of proteins in biomolecular coronas acquired by nanoparticles in biological media contribute to how they are identified by a cell. While numerous studies have investigated protein composition in biomolecular coronas, relatively little detail is known
Cintia Kawai et al.
The journal of physical chemistry. B, 118(41), 11863-11872 (2014-09-24)
Fluorescence quenching of lipid-bound pyrene was used to assess the binding of cytochrome c (cyt c) to liposomes that mimic the inner mitochondrial membrane (IMM) POPC/DOPE/TOCL, with the conditions that it did or did not contain oxidized phosphatidylcholine molecules, i.e.
Functional role of cardiolipin in mitochondrial bioenergetics
Paradies G, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1837(4), 408-417 (2014)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service