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810281P

Avanti

TopFluor® PC

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine, powder

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Synonym(s):
1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphocholine
Empirical Formula (Hill Notation):
C48H83BF2N3O8P
CAS Number:
1246355-63-4
Molecular Weight:
909.97
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810281P-1mg)
pkg of 5 × 1 mg (810281P-5mg)
pkg of 5 × 2 mg (810281P-10mg)

manufacturer/tradename

Avanti Polar Lipids 810281P

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholines (PC) are the building blocks of eukaryotic membranes. It is also found at high levels in Caenorhabditis elegans lipid extracts. PC is an important component of the mucosal layer of the colon. It is a strong bilayer-forming lipid.

Application

TopFluor® PC may be used to test the incorporation of circulating phosphatidylcholine into the myelin sheath. It may also be used in liposome generation.

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

5 mL Amber Glass Screw Cap Vial (810281P-10mg)
5 mL Amber Glass Screw Cap Vial (810281P-1mg)
5 mL Amber Glass Screw Cap Vial (810281P-5mg)

Legal Information

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Membranes of Cells (2016)
Integrative Medicine - E-Book (2017)
Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Conrad KS, et al.
Nature Communications, 8(1), 1908-1908 (2017)
Optimizing a ultrahigh pressure liquid chromatography-time of flight-mass spectrometry approach using a novel sub-2 mum core-shell particle for in depth lipidomic profiling of Caenorhabditis elegans
Witting M, et al.
Journal of Chromatography A, 1359(1), 91-99 (2014)
Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy
Fledrich R, et al.
Nature Communications, 9(1), 3025-3025 (2018)
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