810187P
Avanti
TopFluor® PI
Avanti Polar Lipids 810187P, powder
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Synonym(s):
1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol (ammonium salt)
Empirical Formula (Hill Notation):
C50H84BF2N4O14P
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 50 μg (with stopper and crimp cap (810187P-50ug))
manufacturer/tradename
Avanti Polar Lipids 810187P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol.
Application
TopFluor® PI or 1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol (ammonium salt) has been used as a fluorescent lipid in living cells to analyse the cellular localization of phosphatidylinositol (PI).
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810187P-50ug)
Legal Information
TopFluor is a registered trademark of Avanti Polar Lipids, Inc.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Lipids of membranes: Chemistry, biological role and applications as drug carriers
Hatziantonioy S and Demetzos C
Studies in Natural Products Chemistry, 34, 173-202 (2009)
Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane.
James PZ, et al.
The Journal of Cell Biology, 219(3), e201906127-e201906127 (2020)
James P Zewe et al.
The Journal of cell biology, 219(3) (2020-03-27)
The polyphosphoinositides (PPIn) are central regulatory lipids that direct membrane function in eukaryotic cells. Understanding how their synthesis is regulated is crucial to revealing these lipids' role in health and disease. PPIn are derived from the major structural lipid, phosphatidylinositol
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