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810162P

Avanti

14:0-12:0 NBD PG

Avanti Polar Lipids 810162P, powder

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Synonym(s):
1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-[phospho-rac-(1-glycerol)] (ammonium salt)
Empirical Formula (Hill Notation):
C38H68N5O13P
CAS Number:
384833-03-8
Molecular Weight:
833.95
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810162P-1mg)

manufacturer/tradename

Avanti Polar Lipids 810162P

shipped in

dry ice

storage temp.

−20°C

General description

NBD PG is a fluorophore having fluorescent 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) label attached to phosphatidylglycerol (PG). PG is the second most abundant surfactant phospholipid.

Biochem/physiol Actions

7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) labeled fluorescence lipids are used to study the organization of membranes, micelles and reverse micelles. Phosphatidylglycerol (PG) is involved in alveolar stability and plays a vital role in the regulation of innate immune response.

Packaging

5 mL Amber Glass Screw Cap Vial (810162P-1mg)

Regulatory Information

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H Raghuraman et al.
Biochimica et biophysica acta, 1768(5), 1258-1267 (2007-03-17)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. The NBD group of acyl chain labeled NBD lipids is known
Marianna Agassandian et al.
Biochimica et biophysica acta, 1831(3), 612-625 (2012-10-03)
Pulmonary surfactant is essential for life and is composed of a complex lipoprotein-like mixture that lines the inner surface of the lung to prevent alveolar collapse at the end of expiration. The molecular composition of surfactant depends on highly integrated

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