810156C
Avanti
18:1-12:0 NBD PE
Avanti Polar Lipids 810156C
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1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine
C41H70N5O11P
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Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810156C-1mg)
manufacturer/tradename
Avanti Polar Lipids 810156C
concentration
1 mg/mL (810156C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is localized at the membrane interface. Fluorescent NBD label is covalently linked to the headgroup of phosphatidylethanolamine. Phosphoethanolamine is mostly present in brain and is the second most abundant, metabolically related aminophospholipid.
Application
18:1-06:0 NBD PE may be used as a component of liposome in cross-linking experiment and to determine M13 coat protein selectivity toward phospholipids headgroups.
Biochem/physiol Actions
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a key role as a fluorescent analog in the studies of organization and dynamics of membranes. NBD PE contributes in monitoring Red edge excitation shift (REES) effects with the unique motional and dielectric properties it possesses.
Packaging
5 mL Amber Glass Screw Cap Vial (810156C-1mg)
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
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Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
Journal of biological and chemical chronicles, 282(52), 37298-37302 (2007)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Biochimica et Biophysica Acta, 1861(6), 1152-1161 (2019)
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
Biophysical Journal, 282(52), 37298-37302 (2007)
Fluorescent methods to study biological membranes, 37-50 (2012)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.], 67(6), 481-487 (2013)
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