All Photos(2)
Synonym(s):
1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine
Empirical Formula (Hill Notation):
C35H58N5O11P
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810155P-1mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labelled lipid with NBD attached to phosphatidylethanolamine. It is localized at the membrane interface. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid and is mostly enriched in brain.
Application
18:1-06:0 NBD PE may be used to analyse the temporal fluorescent pattern of cholesterol-E- Nitrobenzoxadiazole (Chol-E-NBD).
Biochem/physiol Actions
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is used as a fluorescent analog in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) functions as a substrate for a number of phospholipids of the cell membrane.
Packaging
5 mL Amber Glass Screw Cap Vial (810155P-1mg)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Fluorescent methods to study biological membranes, 37-50 (2012)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine & Preventive Nutrition, 67(6), 481-487 (2013)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochim. Biophys. Acta Gen. Subj., 1861(6), 1152-1161 (2019)
Synthesis and validation of novel cholesterol-based fluorescent lipids designed to observe the cellular trafficking of cationic liposomes
Kim BK, et al.
Bioorganic & Medicinal Chemistry, 25(18), 3893-3896 (2015)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochim. Biophys. Acta Gen. Subj., 1831(3), 543-554 (2013)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service