All Photos(2)
Synonym(s):
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt)
Empirical Formula (Hill Notation):
C43H78N5O11P
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810144P-1mg)
pkg of 5 × 1 mg (810144P-5mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
General description
16:0 NBD PE is a headgroup labelled fluorescent phospholipid. L-α-Phosphatidylethanolamine (PE) is the most abundant phospholipid in bacteria and the second most abundant in animals, plants and yeast.
Application
16:0 NBD PE is suitable:
- for use in the bilayer, as fluorescent probe, together with encapsulated doxorubicin (DXR) for the preparation of planar-supported lipid bilayers (PSLB) of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)
- used in fluorescence control experiment
- for labelling giant plasma membrane vesicles
Biochem/physiol Actions
L-α-Phosphatidylethanolamine maintains membrane integrity.
Packaging
5 mL Amber Glass Screw Cap Vial (810144P-1mg)
5 mL Amber Glass Screw Cap Vial (810144P-5mg)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Federico Mazur et al.
Langmuir : the ACS journal of surfaces and colloids (2020-02-26)
Synthetic micromotors are evaluated extensively in a range of biomedical, microscale transport, and environmental applications. Fundamental insight into micromotors that exhibit locomotion due to triggered disintegration of their associated liposomes is provided. Directed self-propulsion is observed when the lipid vesicles
1, 2-diacyl-phosphatidylcholine flip-flop measured directly by sum-frequency vibrational spectroscopy
Liu J and Conboy JC
Biophysical Journal, 89(4), 2522-2532 (2005)
Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles
Sengupta P, et al.
Biochimica et Biophysica Acta - Biomembranes, 1778(1), 20-32 (2008)
Mesha Saeed et al.
International journal of nanomedicine, 14, 2069-2089 (2019-04-17)
Melanoma is the most aggressive form of skin cancer. Chemotherapy at a late stage fails due to low accumulation in tumors, indicating the need for targeted therapy. To increase drug uptake by tumor cells, we have targeted doxorubicin-containing liposomes using
Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response
Saeed M, et al.
International journal of nanomedicine, 14, 2069-2069 (2019)
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