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Safety Information

810123C

Avanti

14:0-12:0 NBD PC

Avanti Research™ - A Croda Brand 810123C

Synonym(s):

1-Myristoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-Glycero-3-Phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C40H70N5O11P
CAS Number:
153597-84-3
Molecular Weight:
827.98
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810123C-1mg)
pkg of 5 × 2 mL (810123C-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810123C

concentration

1 mg/mL (810123C-10mg)
1 mg/mL (810123C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a prime metabolite of glycerolipid metabolism in eukaryotes. It is a present in the mucosal layer of the colon. NBD PC contains 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) covalently attached to phosphatidylcholine.

Application

14:0-12:0 NBD PC is suitable for the determination of in vitro Phospholipase D (PLD) activity.

Biochem/physiol Actions

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) is a strong bilayer-forming lipid and used as a fluorescent probe in biological membranes to study the cellular processes.

Packaging

5 mL Amber Glass Screw Cap Vial (810123C-10mg)
5 mL Amber Glass Screw Cap Vial (810123C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

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Takeshi Yamaguchi et al.
Plant physiology, 150(1), 308-319 (2009-03-17)
Phospholipase D (PLD) plays an important role in plants, including responses to abiotic as well as biotic stresses. A survey of the rice (Oryza sativa) genome database indicated the presence of 17 PLD genes in the genome, among which OsPLDalpha1
Eric Oropeza-Guzman et al.
Langmuir : the ACS journal of surfaces and colloids, 35(50), 16528-16535 (2019-11-21)
We took advantage of the microflow hydrodynamics in the evaporation of sessile droplets to increase the height uniformity of thin lipid films for the subsequent electroformation of defect-free giant unilamellar vesicles (GUV). By serially casting progressively larger liposome suspension droplets
Luís M S Loura et al.
Biochimica et biophysica acta, 1778(2), 491-501 (2007-11-21)
We present a combined theoretical (molecular dynamics, MD) and experimental (differential scanning calorimetry, DSC) study of the effect of 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) acyl chain-labeled fluorescent phospholipid analogs (C6-NBD-PC and C12-NBD-PC) on 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers. DSC measurements reveal that <1 mol% of
César Botella et al.
Progress in lipid research, 65, 12-23 (2016-11-23)
In plant cells, phosphatidylcholine (PC) is a major glycerolipid of most membranes but practically lacking from the plastid internal membranes. In chloroplasts, PC is absent from the thylakoids and the inner envelope membrane. It is however the main component of
Jelske N van der Veen et al.
Biochimica et biophysica acta. Biomembranes, 1859(9 Pt B), 1558-1572 (2017-04-16)
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis. In recent

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