791644C
Avanti
18:1-d7 Lyso PE
Avanti Polar Lipids 791644C
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Synonym(s):
1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine
Empirical Formula (Hill Notation):
C23H39D7NO7P
Recommended Products
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (791644C-1mg)
manufacturer/tradename
Avanti Polar Lipids 791644C
concentration
1 mg/mL (791644C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
18:1-d7 Lyso PE (1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The glycerol is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylethanolamine (LPE) is generated from phosphatidylethanolamine by the action of enzyme phospholipase A2.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH® LIPIDOMIX® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
Application
18:1-d7 Lyso PE (1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine) has been used as a component of extraction solvent for lipid isolation from biological samples. It has also been used as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis.
Biochem/physiol Actions
Lysophosphatidylethanolamine (LPE) plays a key role in neuronal differentiation in PC12 cells. It possesses antibacterial and antifungal activity. LPE also favour the calcium transport through G-protein-coupled receptor (GPCR).
Packaging
5 mL Clear Glass Sealed Ampule (791644C-1mg)
Legal Information
LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.
also commonly purchased with this product
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Flash Point(F)
does not flash
Flash Point(C)
does not flash
Regulatory Information
危险化学品
易制毒化学品（2类）
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Caixia Ren et al.
Lipids in health and disease, 17(1), 22-22 (2018-02-06)
Migraine is a prevalent, disabling type of primary headache disorder associated with a high socioeconomic burden. The clinical management of migraine is challenging. This study was to identify potential serum lipidomic biomarkers of migraine. The serum lipidomic profile of migraine
Kumiko Makide et al.
Prostaglandins & other lipid mediators, 89(3-4), 135-139 (2009-05-12)
It is now widely accepted that lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G-protein-coupled receptors. Notably, recent studies of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have revealed their essential roles in vivo. On
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Florian Geltinger et al.
GeroScience, 42(1), 19-38 (2019-11-05)
Originally Lipid droplets (LDs) were considered as being droplets for lipid storage only. Increasing evidence, however, demonstrates that LDs fulfill a pleiotropy of additional functions. Among them is the modulation of protein as well as lipid homeostasis. Under unfavorable pro-oxidative
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