Skip to Content
Merck
CN
All Photos(1)

Documents

700156P

Avanti

20α-hydroxycholesterol

Avanti Polar Lipids 700156P, powder

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
5-cholestene-3α,20α-diol
Empirical Formula (Hill Notation):
C27H46 O2
CAS Number:
516-72-3
Molecular Weight:
402.65
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (700156P-10mg)
pkg of 1 × 5 mg (700156P-5mg)

manufacturer/tradename

Avanti Polar Lipids 700156P

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C27H46O2/c1-18(2)7-6-14-27(5,29)24-11-10-22-21-9-8-19-17-20(28)12-15-25(19,3)23(21)13-16-26(22,24)4/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t20-,21-,22-,23-,24-,25-,26-,27-/m0/s1

InChI key

MCKLJFJEQRYRQT-APGJSSKUSA-N

Application

20α-hydroxycholesterol or 5-cholestene-3α,20α-diol has been used to study the role of oxysterols on mammalian immune function.

Packaging

5 mL Amber Glass Screw Cap Vial (700156P-10mg)
5 mL Amber Glass Screw Cap Vial (700156P-5mg)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Michael E Abrams et al.
Nature microbiology, 5(7), 929-942 (2020-04-15)
Cholesterol 25-hydroxylase (CH25H) is an interferon-stimulated gene that converts cholesterol to the oxysterol 25-hydroxycholesterol (25HC). Circulating 25HC modulates essential immunological processes including antiviral immunity, inflammasome activation and antibody class switching; and dysregulation of CH25H may contribute to chronic inflammatory disease

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service