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Merck
CN

330707

Avanti

SPLASH LIPIDOMIX Mass Spec Standard

Avanti Research - A Croda Brand

Synonym(s):

SPLASH LIPIDOMIX Mass Spec Standard, Single-vial Prepared Lipidomic Analytical Standard for Human plasma lipids

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About This Item

NACRES:
NA.25
UNSPSC Code:
41116107
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Product Name

SPLASH LIPIDOMIX Mass Spec Standard, Avanti Research - A Croda Brand

form

methanol solution

packaging

pkg of 1 × 1 mL (330707-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

1 mg/mL (330707-1EA)

technique(s)

mass spectrometry (MS): suitable

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

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Application

SPLASH LIPIDOMIX Mass Spec Standard has been used:
  • as an internal standard for non-alcoholic fatty liver disease (NAFLD) signature analysis from mice and human samples
  • as an internal standard in the quantification of phospholipids from duodenum, liver, and adipose tissue using ultra performance liquid chromatography quadrupole-time of-flight mass spectrometry (UPLC-q-Tof MS)
  • in human cell lines prior to lipid analysis by liquid chromatography-mass spectrometry (LC-MS) analysis

Features and Benefits

  • Save time: pre-mixed internal standards.
  • Save money: 1 vial is sufficient for 100 plasma samples.
  • Exact concentrations provided for quantitative lipidomic analysis.
  • Applicable to multiple MS approaches.
  • Concentration of each lipid class optimized for plasma analysis.

General description

Make a splash in your lab and dive right into Lipidomics with our easy to use mixture of deuterium labeled lipids. The SPLASH LIPIDOMIX Mass Spec Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample. This internal standard mixture was developed in collaboration with Kim Ekroos (Zora Biosciences).

Other Notes

The SPLASH LIPIDOMIX Mass Spec Standard is supplied in 1 mL of methanol and contains the following components:

Mixture ComponentTarget Conc. (μg/mL)
  • 15:0-18:1(d7) PC160
  • 15:0-18:1(d7) PE5
  • 15:0-18:1(d7) PS5
  • 15:0-18:1(d7) PG30
  • 15:0-18:1(d7) PI10
  • 15:0-18:1(d7) PA7
  • 18:1(d7) LPC25
  • 18:1(d7) LPE5
  • 18:1(d7) Chol Ester350
  • 18:1(d7) MG2
  • 15:0-18:1(d7) DG10
  • 15:0-18:1(d7)-15:0 TG55
  • 18:1(d9) SM30
  • Cholesterol (d7)100

Packaging

2 mL Amber Glass Sealed Ampule (330707-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品
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Bobbie-Jo M Webb-Robertson et al.
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Journal of lipid research, 59(10), 2001-2017 (2018-08-18)
Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) offers insights into individual metabolism and physiology in health and disease. Disturbances in the
Naren Gajenthra Kumar et al.
PloS one, 13(10), e0206606-e0206606 (2018-11-01)
Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the potential for use in developing

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