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About This Item
NACRES:
NA.25
UNSPSC Code:
41116107
form
methanol solution
packaging
pkg of 1 × 1 mL (330707-1EA)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (330707-1EA)
technique(s)
mass spectrometry (MS): suitable
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
General description
Make a splash in your lab and dive right into Lipidomics with our easy to use mixture of deuterium labeled lipids. The SPLASH™ LIPIDOMIX™ Mass Spec Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample. This internal standard mixture was developed in collaboration with Kim Ekroos (Zora Biosciences).
Application
SPLASH™ LIPIDOMIX™ Mass Spec Standard has been used:
- as an internal standard for non-alcoholic fatty liver disease (NAFLD) signature analysis from mice and human samples
- as an internal standard in the quantification of phospholipids from duodenum, liver, and adipose tissue using ultra performance liquid chromatography quadrupole-time of-flight mass spectrometry (UPLC-q-Tof MS)
- in human cell lines prior to lipid analysis by liquid chromatography-mass spectrometry (LC-MS) analysis
Features and Benefits
- Save time: pre-mixed internal standards.
- Save money: 1 vial is sufficient for 100 plasma samples.
- Exact concentrations provided for quantitative lipidomic analysis.
- Applicable to multiple MS approaches.
- Concentration of each lipid class optimized for plasma analysis.
Packaging
2 mL Amber Glass Sealed Ampule (330707-1EA)
Other Notes
The SPLASH LIPIDOMIX Mass Spec Standard is supplied in 1 mL of methanol and contains the following components:
Mixture ComponentTarget Conc. (μg/mL)
Mixture ComponentTarget Conc. (μg/mL)
- 15:0-18:1(d7) PC160
- 15:0-18:1(d7) PE5
- 15:0-18:1(d7) PS5
- 15:0-18:1(d7) PG30
- 15:0-18:1(d7) PI10
- 15:0-18:1(d7) PA7
- 18:1(d7) LPC25
- 18:1(d7) LPE5
- 18:1(d7) Chol Ester350
- 18:1(d7) MG2
- 15:0-18:1(d7) DG10
- 15:0-18:1(d7)-15:0 TG55
- 18:1(d9) SM30
- Cholesterol (d7)100
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
Kit Components Also Available Separately
Product No.
Description
SDS
- 791637C15:0-18:1-d7-PC, Avanti Research™ - A Croda Brand 160μg/mL
- 791638C15:0-18:1-d7-PE, Avanti Research™ - A Croda Brand 5μg/mL
- 791639C15:0-18:1-d7-PS, Avanti Research™ - A Croda Brand 5μg/mL
- 791640C15:0-18:1-d7-PG, Avanti Research™ - A Croda Brand 791640C 30μg/mL
- 791641C15:0-18:1-d7-PI, Avanti Research™ - A Croda Brand 10μg/mL
- 791642C15:0-18:1-d7-PA, Avanti Research™ - A Croda Brand 7μg/mL
- 791643C18:1-d7 Lyso PC, Avanti Research™ - A Croda Brand 25μg/mL
- 791644C18:1-d7 Lyso PE, Avanti Research™ - A Croda Brand 791644C 5μg/mL
- 791645C18:1-d7-cholesterol, Avanti Research™ - A Croda Brand 791645C 350μg/mL
- 791646C18:1-d7 MG, Avanti Research™ - A Croda Brand 791646C 2μg/mL
- 791647C15:0-18:1-d7 DG, Avanti Research™ - A Croda Brand 791647C 10μg/mL
- 791648C15:0-18:1-d7-15:0 TG, Avanti Research™ - A Croda Brand 791648C 55μg/mL
- 791649C18:1-d9 SM, Avanti Research™ - A Croda Brand 30μg/mL
- 700041Pcholesterol-d7, Avanti Research™ - A Croda Brand 100μg/mL
See All (14)
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Regulatory Information
危险化学品
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Mike Lange et al.
Analytical and bioanalytical chemistry, 412(15), 3573-3584 (2020-04-03)
Lipidomics analysis for large-scale studies aiming at the identification and quantification of natural lipidomes is often performed using LC-MS-based data acquisition. However, the choice of suitable LC-MS method for accurate lipid quantification remains a matter of debate. Here, we performed
Tomoki Naito et al.
eLife, 8 (2019-11-15)
Cholesterol is a major structural component of the plasma membrane (PM). The majority of PM cholesterol forms complexes with other PM lipids, making it inaccessible for intracellular transport. Transition of PM cholesterol between accessible and inaccessible pools maintains cellular homeostasis
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Breast cancer (BC) is the most prevalent type of cancer in women in western countries. BC mortality has not declined despite early detection by screening, indicating the need for better informed treatment decisions. Therefore, a novel noninvasive diagnostic tool for
Metabolomics Profile and Targeted Lipidomics in Multiple Tissues Associated with Feed Efficiency in Beef Steers
Artegoitia VM, et al.
ACS Omega, 4(2), 3973-3982 (2019)
Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism.
Isha H Jain et al.
Cell, 181(3), 716-727 (2020-04-08)
Human cells are able to sense and adapt to variations in oxygen levels. Historically, much research in this field has focused on hypoxia-inducible factor (HIF) signaling and reactive oxygen species (ROS). Here, we perform genome-wide CRISPR growth screens at 21%
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