330707
Avanti
SPLASH® LIPIDOMIX® Mass Spec Standard
Avanti Polar Lipids
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Synonym(s):
SPLASH® LIPIDOMIX® Mass Spec Standard, Single-vial Prepared Lipidomic Analytical Standard for Human plasma lipids
UNSPSC Code:
41116107
NACRES:
NA.25
Recommended Products
form
methanol solution
packaging
pkg of 1 × 1 mL (330707-1EA)
manufacturer/tradename
Avanti Polar Lipids
concentration
1 mg/mL (330707-1EA)
technique(s)
mass spectrometry (MS): suitable
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
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General description
Make a splash in your lab and dive right into Lipidomics with our easy to use mixture of deuterium labeled lipids. The SPLASH® LIPIDOMIX® Mass Spec Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample. This internal standard mixture was developed in collaboration with Kim Ekroos (Zora Biosciences).
Application
SPLASH® LIPIDOMIX® Mass Spec Standard has been used:
- as an internal standard for non-alcoholic fatty liver disease (NAFLD) signature analysis from mice and human samples
- as an internal standard in the quantification of phospholipids from duodenum, liver, and adipose tissue using ultra performance liquid chromatography quadrupole-time of-flight mass spectrometry (UPLC-q-Tof MS)
- in human cell lines prior to lipid analysis by liquid chromatography-mass spectrometry (LC-MS) analysis
Features and Benefits
- Save time: pre-mixed internal standards.
- Save money: 1 vial is sufficient for 100 plasma samples.
- Exact concentrations provided for quantitative lipidomic analysis.
- Applicable to multiple MS approaches.
- Concentration of each lipid class optimized for plasma analysis.
Packaging
2 mL Amber Glass Sealed Ampule (330707-1EA)
Components
The SPLASH LIPIDOMIX Mass Spec Standard is supplied in 1 mL of methanol and contains the following components:
Mixture ComponentTarget Conc. (μg/mL)
Mixture ComponentTarget Conc. (μg/mL)
- 15:0-18:1(d7) PC160
- 15:0-18:1(d7) PE5
- 15:0-18:1(d7) PS5
- 15:0-18:1(d7) PG30
- 15:0-18:1(d7) PI10
- 15:0-18:1(d7) PA7
- 18:1(d7) LPC25
- 18:1(d7) LPE5
- 18:1(d7) Chol Ester350
- 18:1(d7) MG2
- 15:0-18:1(d7) DG10
- 15:0-18:1(d7)-15:0 TG55
- 18:1(d9) SM30
- Cholesterol (d7)100
Legal Information
LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.
Kit Components Also Available Separately
Product No.
Description
SDS
- 791637C15:0-18:1-d7-PC, Avanti Polar Lipids 160μg/mLSDS
- 791638C15:0-18:1-d7-PE, Avanti Polar Lipids 5μg/mLSDS
- 791639C15:0-18:1-d7-PS, Avanti Polar Lipids 5μg/mLSDS
- 791640C15:0-18:1-d7-PG, Avanti Polar Lipids 791640C 30μg/mLSDS
- 791641C15:0-18:1-d7-PI, Avanti Polar Lipids 10μg/mLSDS
- 791642C15:0-18:1-d7-PA, Avanti Polar Lipids 7μg/mLSDS
- 791643C18:1-d7 Lyso PC, Avanti Polar Lipids 25μg/mLSDS
- 791644C18:1-d7 Lyso PE, Avanti Polar Lipids 791644C 5μg/mLSDS
- 791645C18:1-d7-cholesterol, Avanti Polar Lipids 791645C 350μg/mLSDS
- 791646C18:1-d7 MG, Avanti Polar Lipids 791646C 2μg/mLSDS
- 791647C15:0-18:1-d7 DG, Avanti Polar Lipids 791647C 10μg/mLSDS
- 791648C15:0-18:1-d7-15:0 TG, Avanti Polar Lipids 791648C 55μg/mLSDS
- 791649C18:1-d9 SM, Avanti Polar Lipids 30μg/mLSDS
- 700041Pcholesterol-d7, Avanti Polar Lipids 100μg/mLSDS
See All (14)
also commonly purchased with this product
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Target Organs
Eyes,Central nervous system
WGK
WGK 2
Flash Point(F)
49.5 °F
Flash Point(C)
9.7 °C
Regulatory Information
危险化学品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Tomoki Naito et al.
eLife, 8 (2019-11-15)
Cholesterol is a major structural component of the plasma membrane (PM). The majority of PM cholesterol forms complexes with other PM lipids, making it inaccessible for intracellular transport. Transition of PM cholesterol between accessible and inaccessible pools maintains cellular homeostasis
Mike Lange et al.
Analytical and bioanalytical chemistry, 412(15), 3573-3584 (2020-04-03)
Lipidomics analysis for large-scale studies aiming at the identification and quantification of natural lipidomes is often performed using LC-MS-based data acquisition. However, the choice of suitable LC-MS method for accurate lipid quantification remains a matter of debate. Here, we performed
M A López-Bascón et al.
Analytical and bioanalytical chemistry, 412(2), 489-498 (2019-11-25)
Polar lipids, especially glycerophospholipids, constitute the main components of cell membranes and are precursors of signaling molecules in many cellular and physiological processes. For this reason, the development of methods with high capability for detection of polar lipids in biological
Metabolomics Profile and Targeted Lipidomics in Multiple Tissues Associated with Feed Efficiency in Beef Steers
Artegoitia VM, et al.
ACS Omega, 4(2), 3973-3982 (2019)
Valerie Z Wall et al.
Journal of lipid research, 58(6), 1174-1185 (2017-04-19)
Acyl-CoA thioesterase 7 (ACOT7) is an intracellular enzyme that converts acyl-CoAs to FFAs. ACOT7 is induced by lipopolysaccharide (LPS); thus, we investigated downstream effects of LPS-induced induction of ACOT7 and its role in inflammatory settings in myeloid cells. Enzymatic thioesterase
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