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description
Dox-NP® (Liposomal Encapsulated Doxorubicin)
frozen liposomal suspension (buffer - 10% w/w sucrose, 10 mM histidine ~pH 6.5)
Assay
>99% (HPLC/MS)
form
dispersion
packaging
pkg of 1 × 2 mL (300112S-1EA)
manufacturer/tradename
Avanti Polar Lipids
application(s)
advanced drug delivery
shipped in
dry ice
storage temp.
−20°C
Application
Dox-NP™(2mL vial) is suitable for use:
- in ultraviolet-visible (UV-vis) spectra, cryo-transmission electron microscopy (cryo-TEM) and analytical ultracentrifuge experiments
- in transmission electron microscopy (TEM) imaging studies
- to analyse the effect of gold nanoparticle loaded liposomes on anti-tumor and cytotoxicity properties of DOX-NP on Ehrlich tumor
Biochem/physiol Actions
Dox-NP™ (doxorubicin loaded nanoparticles) is a liposomal drug encapsulating doxorubicin. This encapsulation reduces the side effects of doxorubicin and increases the effective local dose.
Packaging
10 mL amber serum vial (300112S-1EA)
Legal Information
Avanti is a registered trademark of Avanti Polar Lipids, Inc.
Dox-NP is a trademark of Avanti Polar Lipids, Inc.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 1B - Muta. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Analytical ultracentrifugation for analysis of doxorubicin loaded liposomes
Mehn D, et al.
International Journal of Pharmaceutics, 523(1), 320-326 (2017)
Enhanced Ehrlich tumor inhibition using DOX-NP and gold nanoparticles loaded liposomes
Mady MM, et al.
Pakistan Journal of Pharmaceutical Sciences, 1(28), 2321-2325 (2015)
Transmission electron microscopy as a tool for the characterization of soft materials: application and interpretation
Franken LE, et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 4(5), 1600476-1600476 (2017)
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