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190001C

Avanti

Yeast Extract Polar

Avanti Polar Lipids

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Synonym(s):
Yeast Extract Polar, Yeast Polar Lipid Extract (S. cerevisiae)
UNSPSC Code:
12352211
NACRES:
NA.25

form

chloroform solution

packaging

pkg of 1 × 4 mL (190001C-100mg)
pkg of 5 × 4 mL (190001C-500mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

25 mg/mL (190001C-100mg)
25 mg/mL (190001C-500mg)

lipid type

lipid extracts

shipped in

dry ice

storage temp.

−20°C

General description

Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.
Yeast is rich in sphingolipids. The apolar lipids from yeast separate out first during chloroform/methanol extraction. The aqueous phase contains polar lipids. A total of 162 lipids pertaining to 21 lipid classes have been identified in yeast. Phosphatidylinositol comprises the major component of yeast lipid accounting to 17% to 30%.

Application

Yeast Extract Polar has been used as a component of liposome for proteoliposomes preparation.

Biochem/physiol Actions

Yeast lipids serve as model membranes for understanding the lipid raft forming mechanisms. These lipids have the potential to self-organize. The fatty acid composition of polar lipids in yeast are modulated in response to acid stress. The total lipids from yeast are useful in understanding lipid metabolism.

Packaging

5 mL Clear Glass Sealed Ampule (190001C-100mg)
5 mL Clear Glass Sealed Ampule (190001C-500mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

Certificates of Analysis (COA)

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Single-molecule analyses reveal rhomboid proteins are strict and functional monomers in the membrane
Kreutzberger AJB and Urban S
Biophysical Journal, 115(9), 1755-1761 (2018)
Yeast lipids can phase-separate into micrometer-scale membrane domains
Klose C, et al.
The Journal of biological chemistry, 285(39), 30224-30232 (2010)
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry
Ejsing CS, et al.
Proceedings of the National Academy of Sciences of the USA, 106(7), 2136-2141 (2009)
Joël S Bloch et al.
Nature, 579(7799), 443-447 (2020-02-28)
In eukaryotic protein N-glycosylation, a series of glycosyltransferases catalyse the biosynthesis of a dolichylpyrophosphate-linked oligosaccharide before its transfer onto acceptor proteins1. The final seven steps occur in the lumen of the endoplasmic reticulum (ER) and require dolichylphosphate-activated mannose and glucose
Budding Yeast: An ideal backdrop for in vivo lipid biochemistry
Singh P
Frontiers in Cell and Developmental Biology, 4, 156-156 (2017)
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