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131601P

Avanti

L-α-Phosphatidylcholine

95% (Egg), Avanti Polar Lipids, Powder

Synonym(s):

L-α-phosphatidylcholine (95%) (Egg, Chicken)

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About This Item

CAS Number:
97281-44-2
MDL number:
MFCD00077387
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

Egg PC (95%), Avanti Research™ - A Croda Brand

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (131601P-1g)
pkg of 10 × 1 g (131601P-10g)
pkg of 5 × 1 g (131601P-5g)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

General description

l-α-phosphatidylcholine constitutes 20% of the total phospholipids in chicken egg. It has palmitic acid (16:0) and oleic acid (18:1) in at sn-1 and sn-2 positions, respectively.[1]
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.[2]
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

Application

Egg PC (95%) has been used for the reconstitution of purified Kv1.3 into liposomes.[3]
Egg PC (95%) has been used in the synthesis of high-density lipoprotein (HDL) based nanoparticle for nerve growth factor (NGF) encapsulation.[4] It has also been used in the proteoliposome preparation.[5]

Biochem/physiol Actions

Egg PC in its saturated form favors inhibition of cholesterol absorption.[1] It is used in lipid preparation[6] and liposomes for biophysical studies.[2] Egg PC contributes cardiovascular disease (CVD) risk by acting as a substrate for microbes leading to of trimethylamine N-oxide (TMAO) synthesis.[1]

Packaging

125 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-5g)
250 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-10g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (131601P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
    Perez C, et al.
    Structure (2019)
    Preparation and characterization of novel hdl-mimicking nanoparticles for nerve growth factor encapsulation
    Zhu, Jing and Dong, Xiaowei
    Journal of Visualized Experiments, (123), e55584-e55584 (2008)
    A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1. 3
    Bednenko J, et al.
    MAbs, 10(4), 636-650 (2018)
    Characterization of interactions of eggPC lipid structures with different biomolecules
    Chahar FC, et al.
    Chemistry and Physics of Lipids, 210, 60-69 (2018)
    Effects of Cholesterol Concentrations on Egg-phosphatidylcholine-Dihexadecyl-phosphate Liposomes Studied by CW ESR and FT-ESEEM Spectroscopy
    Mirosavljevic K and Noethig-Laslo V
    Croatica Chemica Acta. Arhiv Za Kemiju, 81(4), 631-636 (2008)
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