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Merck
CN

131601C

Avanti

Egg PC (95%)

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylcholine (95%) (Egg, Chicken)

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About This Item

CAS Number:
97281-44-2
MDL number:
MFCD00077387
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

Egg PC (95%), Avanti Research™ - A Croda Brand

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

assay

>99% (TLC)

form

chloroform solution

packaging

pkg of 2 × 20 mL (131601C-1g)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

25 mg/mL (131601C-1g)

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

Application

Egg PC (95%) has been used for the reconstitution of nhTMEM16 into liposomes.
Egg PC (95%) is suitable for the preparation of multi-lamellar liposomes.
Egg PC (95%) is suitable for use in the liposome preparation for the reconstitution of lipid-linked oligosaccharide (LLO) flippase protein, Protein glyocyslaion K (PglK).

Biochem/physiol Actions

Egg L-α-phosphatidylcholine (PC) is used in lipid preparation and liposomes for biophysical studies. It serves as a substrate for microbes for trimethylamine N-oxide (TMAO) synthesis. Egg PC is used as a marker to access cardiovascular disease (CVD) risk.

General description

Egg L-α-phosphatidylcholine (PC) has palmitic acid (16:0) and oleic acid (18:1) at sn-1 and sn-2 positions, respectively. It constitutes 20% of the total phospholipids in egg.
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (131601C-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品
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Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
Kalienkova V, et al.
eLife, 8, e44364-e44364 (2019)
Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
Perez C, et al.
Structure, 27(4), 669-678 (2019)
Characterization of interactions of eggPC lipid structures with different biomolecules
Chahar FC, et al.
Chemistry and Physics of Lipids, 210, 60-69 (2018)
Egg phospholipids and cardiovascular health
Blesso C
Nutrients, 7(4), 2731-2747 (2015)
Effects of Cholesterol Concentrations on Egg-phosphatidylcholine-Dihexadecyl-phosphate Liposomes Studied by CW ESR and FT-ESEEM Spectroscopy
Mirosavljevic K and Noethig-Laslo V
Croatica Chemica Acta. Arhiv Za Kemiju, 81(4), 631-636 (2008)
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