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W700544

Sigma-Aldrich

Acesulfame potassium

≥99%, FG

Synonym(s):

Acesulfame K, 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt

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About This Item

Empirical Formula (Hill Notation):
C4H4KNO4S
CAS Number:
Molecular Weight:
201.24
Beilstein:
3637857
MDL number:
UNSPSC Code:
12352205
E Number:
E 950
NACRES:
NA.21

grade

FG
Halal
Kosher

Quality Level

reg. compliance

EU Regulation 1333/2008 & 178/2002
FDA 21 CFR 117

Assay

≥99%

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

odorless

SMILES string

[K+].CC1=CC(=O)[N-]S(=O)(=O)O1

InChI

1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1

InChI key

WBZFUFAFFUEMEI-UHFFFAOYSA-M

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Application


  • Acesulfame potassium upregulates PD-L1 in HCC cells by attenuating autophagic degradation.: This study reveals that acesulfame potassium can upregulate PD-L1 expression in hepatocellular carcinoma cells by reducing autophagic degradation, which could have implications for cancer immunotherapy (Kim et al., 2024).

  • Sweet taste receptors play roles in artificial sweetener-induced enhanced urine output in mice.: This study explores the role of sweet taste receptors in mediating the increased urine output observed with the consumption of artificial sweeteners like acesulfame potassium in mice (Cai et al., 2024).

  • Molecular docking study of frequently used food additives for selected targets depending on the chromosomal abnormalities they cause.: A molecular docking study that examines the interaction of common food additives, including acesulfame potassium, with specific molecular targets associated with chromosomal abnormalities (Okus et al., 2024).

  • Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method.: This paper presents a novel method for the simultaneous analysis of natural and artificial sweeteners, including acesulfame potassium, in sugar-free beverages and urine samples, enhancing analytical capabilities in food safety and health studies (Cheng et al., 2024).

Other Notes

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WGK

WGK 1


Certificates of Analysis (COA)

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