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Merck
CN

W530098

Naringenin

natural (US), 98%

Synonym(s):

(±)-Naringenin, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4′,5,7-Trihydroxyflavanone

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About This Item

Empirical Formula (Hill Notation):
C15H12O5
CAS Number:
67604-48-2
Molecular Weight:
272.25
PubChem Substance ID:
329830749
UNSPSC Code:
12164502
FEMA Number:
4797
NACRES:
NA.21
EC Number:
266-769-1
MDL number:
MFCD00006844
Organoleptic:
faint
Grade:
natural (US)
Biological source:
Citrus paradisi Macf.
Food allergen:
no known allergens

Key Documents

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Product Name

Naringenin, natural (US), 98%

InChI

1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

InChI key

FTVWIRXFELQLPI-UHFFFAOYSA-N

SMILES string

OC1=CC=C(C=C1)C(C2)OC3=CC(O)=CC(O)=C3C2=O

biological source

Citrus paradisi Macf.

grade

natural (US)

assay

98%

mp

247-250 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

faint

Quality Level

300

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Related Categories

Application

Naringenin has been used in a study to compare its antigenotoxic and antioxidative activity with that of naringenin-oxime.

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

General description

Naringenin is a bioactive flavonoid found in citrus and grapefruit.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBS0093
SHBQ2644
SHBP9990
SHBM4207
SHBL8943

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Antigenotoxic and antioxidant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells
Kocyigit A, et al
Drug and Chemical Toxicology, 39(1), 66-73 (2016)
Xingyuan Shi et al.
Journal of cellular and molecular medicine, 25(5), 2563-2571 (2021-02-02)
Lung cancer is one of the major cause for high-death rate all over the world, due to increased metastasize and difficulties in diagnosis. Naringenin is naturally occurring flavonoid found in various fruits including tomatoes, citrus fruit and figs. Naringenin is
Ruibing Chen et al.
Frontiers in plant science, 9, 789-789 (2018-07-18)
Scutellarin, a flavonoid 7-O-glucuronide, is an essential bioactive compound of Erigeron breviscapus (Vaniot) Hand.-Mazz. used for the treatment of cerebrovascular diseases. However, due to overexploitation and overuse, E. breviscapus is facing the problems of extinction and habitat degradation. In this
Barbara Napoli et al.
Frontiers in neuroscience, 13, 1202-1202 (2019-12-06)
Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominant
Senem Kamiloglu et al.
Journal of the science of food and agriculture, 94(11), 2225-2233 (2014-01-01)
In order to investigate the effect of home processing on the bioaccessibility of health-related constituents of tomatoes, total lycopene, phenolics, flavonoids and antioxidant capacity were determined from seven different tomato products using an in vitro gastrointestinal digestion model. Additionally, the
View All Related Papers

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